1-Aryl-1,2,3,4-tetrahydroisoquinolines as potential antimalarials: synthesis, in vitro antiplasmodial activity and in silico pharmacokinetics... (Publications)
In the present study, twenty-one 1-aryl-6-hydroxy-1,2,3,4-tetrahydroisoquinoline (THIQ) analogues were synthesized by base-catalyzed Pictet-Spengler reaction, and tested in vitro against P. falciparum
<em>Angiostrongylus cantonensis</em> (Nematode: Metastrongyloidea) in molluscs from harbour areas in Brazil (Publications)
Angiostrongylus cantonensis is the most common aetiological agent of human eosinophilic meningoencephalitis. Following a report indicating the presence of this parasite in Brazil in 2007, the present
HIV-related stigma in rural and tribal communities of Maharashtra, India (Publications)
Stigma is a recognized barrier to early detection of HIV and causes great suffering for those affected. This paper examines HIV-related stigma in rural and tribal communities of Maharashtra, an area o
Bromopyrrole alkaloids as lead compounds against protozoan parasites (Publications)
In the present study, 13 bromopyrrole alkaloids, including the oroidin analogs hymenidin (2), dispacamide B (3) and dispacamide D (4), stevensine (5) and spongiacidin B (6), their derivatives lacking
Discovery and evaluation of thiazinoquinones as anti-protozoal agents (Publications)
Pure compound screening has identified the dioxothiazino-quinoline-quinone ascidian metabolite ascidiathiazone A (2) to be a moderate growth inhibitor of Trypanosoma brucei rhodesiense (IC50 3.1 muM)
