Etude suisse sur la pollution de l'air et les maladies respiratoires chez l'adulte (SAPALDIA) (Publications)
Long-term health effects of moderate ambient air pollution are rarely investigated. In Switzerland, no large-scale study has addressed this issue so far. Important results of the Swiss Study on Air Po
Investigation of the concentration of bacteria and their cell envelope components in indoor air in two elementary schools (Publications)
Bacterial cell envelope components are widely distributed in airborne dust, where they act as inflammatory agents causing respiratory symptoms. Measurements of these agents and other environmental fac
Cleavage of trypanosome surface glycoproteins by alkaline trypsin-like enzyme(s) in the midgut of <em>Glossina morsitans</em> (Publications)
EP and GPEET procyclin, the major surface glycoproteins of procyclic forms of Trypanosoma brucei, are truncated by proteases in the midgut of the tsetse fly Glossina morsitans morsitans. We show that
Synthesis of a series of N(6)-substituted adenosines with activity against trypanosomatid parasites (Publications)
The involvement of purine salvage in the accumulation of current trypanocidal drugs is important for the treatment of African sleeping sickness. The substrate specificity of essential nucleoside trans
Use of personal measurements for ozone exposure assessment: a pilot study (Publications)
During summer 1991, we collected indoor, outdoor, and personal ozone concentration data as well as time-activity data in State College, Pennsylvania. These concentrations were measured for 23 children
Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas (Publications)
Cruciferous vegetables, especially broccoli, may prevent cancer through anticarcinogenic compounds. For example, broccoli contains isothiocyanates that induce carcinogen-detoxifying enzymes. Glutathio
The U.S. Environmental Protection Agency Particulate Matter Health Effects Research Centers Program: a midcourse report of status, progress, and plans (Publications)
In 1998 Congress mandated expanded U.S. Environmental Protection Agency (U.S. EPA) health effects research on ambient air particulate matter (PM) and a National Research Council (NRC) committee to pro
Comparison of the in vitro drug sensitivity of <em>Trypanosoma brucei gambiense</em> strains from West and Central Africa isolated in the periods... (Publications)
The situation of human African trypanosomiasis remains serious with one of the main threats being the increasing number of relapses or treatment failures after melarsoprol treatment. In order to inves
