Beyond malaria: causes of fever in outpatient Tanzanian children (Publications)
BACKGROUND: As the incidence of malaria diminishes, a better understanding of nonmalarial fever is important for effective management of illness in children. In this study, we explored the spectrum of
Enhancing the usefulness of cross dehydrogenative coupling reactions with a removable protecting group (Publications)
A removable protecting group has been identified that allows the products of widely-used cross dehydrogenative couplings to be synthetically elaborated. The method can be used with enantiopure amines
Intergovernmental relations and long term care reforms: lessons from the Italian case (Publications)
The article aims at analysing the reasons why Italy failed to reform Long Term Care (LTC) policies, focusing on an aspect which has been overlooked: the interplay between LTC policies and the intergov
The prevalence and distribution of food sensitization in european adults (Publications)
BACKGROUND: Complaints of 'food allergy' are increasing. Standardized surveys of IgE sensitization to foods are still uncommon and multicountry surveys are rare. We have assessed IgE sensitization to
Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of <em>Plasmodium falciparum</em> enoyl-ACP-reductase... (Publications)
Malaria, a disease of worldwide significance, is responsible for over one million deaths annually. The liver-stage of Plasmodium's life cycle is the first, obligatory, but clinically silent step in ma
Substituted 2-phenyl-imidazopyridines: a new class of drug leads for human African trypanosomiasis (Publications)
A phenotypic screen of a compound library for antiparasitic activity on Trypanosoma brucei, the causative agent of human African trypanosomiasis, led to the identification of substituted 2-(3-aminophe
Use of B-type natriuretic peptide for the management of women with dyspnea (Publications)
In studies with predominately male patients, B-type natriuretic peptide (BNP) levels have been shown to be helpful in the evaluation and management of patients who present with acute dyspnea. The effe
Activity of diimidazoline amides against <em>African trypanosomiasis</em> (Publications)
We identified several diimidazoline mono- and diamides that were as potent as pentamidine against Trypanosoma brucei rhodesiense in vitro. All of these were also less cytotoxic than pentamidine, but n
The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer) (Publications)
Praziquantel has been the mainstay of schistosomiasis control since 1984 and widely distributed since 2006 through 'preventive chemotherapy' programmes to school-aged children or at-risk populations.
