Ro 15-0216: a nitroimidazole compound active in vitro against human and animal pathogenetic African trypanosomes (Publications)
In vitro systems for the continuous cultivation of Trypanosoma brucei brucei, T. b. gambiense, T. b. rhodesiense, T. congolense and T. vivax were used to determine the antitrypanosomal activity of the
Antimalarial and antitubercular nostocarboline and eudistomin derivatives: synthesis, in vitro and in vivo biological evaluation (Publications)
The synthesis of nine nostocarboline derivatives with substitutions of the 2-methyl group by alkyl, aryl and functionalized residues, 10 symmetrical bis cationic dimers linking 6-Cl-norharmane through
Does the 'hygiene hypothesis' provide an explanation for the relatively low prevalence of asthma in Bangladesh? (Publications)
The prevalence of childhood asthma in Bangladesh is much lower than in developed countries, but similar to those of other countries in this region like Pakistan and India.1 These differences in asthma
Environmental exposure to endotoxin and other microbial products and the decreased risk of childhood atopy: evaluating developments since April 2002 (Publications)
PURPOSE OF REVIEW: The hygiene hypothesis proposes an association between the change in exposure to microbes and the increased incidence of atopic diseases in recent decades. Exposure to microbes and
Environmental exposure to endotoxin and its relation to asthma in school-age children (Publications)
BACKGROUND: In early life, the innate immune system can recognize both viable and nonviable parts of microorganisms. Immune activation may direct the immune response, thus conferring tolerance to alle
The N-terminal domain of <em>Plasmodium falciparum</em> circumsporozoite protein represents a target of protective immunity (Publications)
The N-terminal domain of the circumsporozoite protein (CSP) has been largely neglected in the search for a malaria vaccine in spite of being a target of inhibitory antibodies and protective T cell res
