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1. Nifurtimox-eflornithine combination therapy for second-stage African <em>Trypanosoma brucei gambiense</em> trypanosomiasis: a multicentre, randomised,... (Publications)

   Nifurtimox-eflornithine combination therapy for second-stage African <em>Trypanosoma brucei gambiense</em> trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial

   Pertinence:

   BACKGROUND: Human African trypanosomiasis (HAT; sleeping sickness) caused by Trypanosoma brucei gambiense is a fatal disease. Current treatment options for patients with second-stage disease are toxic

2. Human antibodies to recombinant protein constructs of <em>Plasmodium falciparum</em> Apical Membrane Antigen 1 (AMA1) and their associations with... (Publications)

   Human antibodies to recombinant protein constructs of <em>Plasmodium falciparum</em> Apical Membrane Antigen 1 (AMA1) and their associations with protection from malaria

   Pertinence:

   Serum antibodies from 1071 people in two Kenyan villages were assayed using eight different recombinant Apical Membrane Antigen 1 (AMA1) protein constructs to investigate their role in naturally acqui

3. Transmission dynamics of highly pathogenic avian influenza at lake constance (Europe) during the outbreak of winter 2005-2006 (Publications)

   Transmission dynamics of highly pathogenic avian influenza at lake constance (Europe) during the outbreak of winter 2005-2006

   Pertinence:

   Highly pathogenic avian influenza virus (HPAI) H5N1 poses a serious threat to domestic animals. Despite the large number of studies on influenza A virus in waterbirds, little is still known about the

4. Lectin binding to secretory structures, the cuticle and the surface coat of <em>Toxocara canis </em>infective larvae (Publications)

   Lectin binding to secretory structures, the cuticle and the surface coat of <em>Toxocara canis </em>infective larvae

   Pertinence:

5. Malaria-infected mice are cured by oral administration of new artemisinin derivatives (Publications)

   Malaria-infected mice are cured by oral administration of new artemisinin derivatives

   Pertinence:

   In four or five chemical steps from the 1,2,4-trioxane artemisinin, a new series of 23 trioxane dimers has been prepared. Eleven of these new trioxane dimers cure malaria-infected mice via oral dosing

6. IGFBP2 and IGFBP3 protein expressions in human breast cancer: association with hormonal factors and obesity (Publications)

   IGFBP2 and IGFBP3 protein expressions in human breast cancer: association with hormonal factors and obesity

   Pertinence:

   PURPOSE: The insulin-like growth factor (IGF) signaling system is involved in breast cancer initiation and progression. The prognostic relevance of tumor expression patterns of IGFI-related proteins r

7. Antiprotozoal activities of heterocyclic-substituted xanthones from the marine-derived fungus <em>Chaetomium</em> sp (Publications)

   Antiprotozoal activities of heterocyclic-substituted xanthones from the marine-derived fungus <em>Chaetomium</em> sp

   Pertinence:

   Investigations of the marine-derived fungus Chaetomium sp. led to the isolation of the new natural products chaetoxanthones A, B, and C (1-3). Compounds 1 and 2 are substituted with a dioxane/tetrahyd

8. Induction of resistance to melarsenoxide cysteamine (Mel Cy) in <em>Trypanosoma brucei brucei</em> (Publications)

   Induction of resistance to melarsenoxide cysteamine (Mel Cy) in <em>Trypanosoma brucei brucei</em>

   Pertinence:

9. Ferrocenyl derivatives of the anthelmintic praziquantel: design, synthesis and biological evaluation (Publications)

   Ferrocenyl derivatives of the anthelmintic praziquantel: design, synthesis and biological evaluation

   Pertinence:

   The design, synthesis and biological evaluation of eighteen ferrocenyl derivatives (4A-12A and 4B-12B) of the most-well known drug against schistosomiasis, namely praziquantel (PZQ), are reported. The

10. Qu'est-ce qu'une régression logistique? (Publications)

    Qu'est-ce qu'une régression logistique?

    Pertinence: