Genetic regulation of<em> IL1RL1</em> methylation and IL1RL1-a protein levels in asthma (Publications)
Interleukin-1 receptor-like 1 (IL1RL1) is an important asthma gene. (Epi)genetic regulation of IL1RL1 protein expression has not been established. We assessed the association between IL1RL1 single nuc
TnSeq of <em>Mycobacterium tuberculosis</em> clinical isolates reveals strain-specific antibiotic liabilities (Publications)
Once considered a phenotypically monomorphic bacterium, there is a growing body of work demonstrating heterogeneity among Mycobacterium tuberculosis (Mtb) strains in clinically relevant characteristic
Diurnal variability of transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland (Publications)
BACKGROUND: Most epidemiological noise studies consider 24h average noise exposure levels. Our aim was to exploratively analyze the impact of noise exposure at different time windows during day and ni
Effect of offering same-day ART vs usual health facility referral during home-based HIV testing on linkage to care and viral suppression among adults... (Publications)
Importance: Home-based HIV testing is a frequently used strategy to increase awareness of HIV status in sub-Saharan Africa. However, with referral to health facilities, less than half of those who tes
Comparison of antigen and antibody responses in repeat lymphatic filariasis transmission assessment surveys in American Samoa (Publications)
BACKGROUND: Current WHO recommendations for lymphatic filariasis (LF) surveillance advise programs to implement activities to monitor for new foci of transmission after stopping mass drug administrati
Characterization of the rhesus macaque (<em>Macaca mulatta</em>) scrub typhus model: susceptibility to intradermal challenge with the human pathogen... (Publications)
BACKGROUND: Scrub typhus is an important endemic disease in tropical Asia caused by Orientia tsutsugamushi for which no effective broadly protective vaccine is available. The successful evaluation of