Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1<em>H</em>-1,2,3-triazoles (Publications)
Novel dicationic triazoles 1-60 were synthesized by the Pinner method from the corresponding dinitriles, prepared via the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC). The type and the place
A survey of bovine cysticercosis/human taeniosis in Northern Turkana District, Kenya (Publications)
Bovine cysticercosis is a zoonosis that is mainly of socioeconomic and public health importance. A survey of this disease was carried out in Northern Turkana District, Kenya to estimate the prevalence
Design and synthesis of a series of melamine-based nitroheterocycles with activity against trypanosomatid parasites (Publications)
The parasites that give rise to human African trypanosomiasis (HAT) are auxotrophs for various nutrients from the human host, including purines. They have specialist nucleoside transporters to import
O-alkoxyamidine prodrugs of furamidine: in vitro transport and microsomal metabolism as indicators of in vivo efficacy in a mouse model of... (Publications)
Five O-alkoxyamidine analogues of the prodrug 2,5-bis[4-methoxyamidinophenyl]furan were synthesized and evaluated against Trypanosoma brucei rhodesiense in the STIB900 mouse model by oral administrati
Prevalence and implications of multiple-strain infections (Publications)
Infections frequently contain multiple strains (genotypes) of the same pathogen, yet they are still usually treated as uniform entities. In this Review, we discuss problems with inconsistent definitio
