Recherche de *.

1. Single ascending dose pharmacokinetic study of tribendimidine in <em>Opisthorchis viverrini</em>-infected patients (Publications)

   Single ascending dose pharmacokinetic study of tribendimidine in <em>Opisthorchis viverrini</em>-infected patients

   Pertinence:

   OBJECTIVES: Praziquantel is the only drug available for treatment of Opisthorchis viverrini infections. Tribendimidine has emerged as potential treatment alternative, however its pharmacokinetic (PK)

2. Mapping intra-urban malaria risk using high resolution satellite imagery: a case study of Dar es Salaam (Publications)

   Mapping intra-urban malaria risk using high resolution satellite imagery: a case study of Dar es Salaam

   Pertinence:

   BACKGROUND: With more than half of Africa's population expected to live in urban settlements by 2030, the burden of malaria among urban populations in Africa continues to rise with an increasing numbe

3. Health in times of uncertainty in the eastern Mediterranean region, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013 (Publications)

   Health in times of uncertainty in the eastern Mediterranean region, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013

   Pertinence:

   BACKGROUND: The eastern Mediterranean region is comprised of 22 countries: Afghanistan, Bahrain, Djibouti, Egypt, Iran, Iraq, Jordan, Kuwait, Lebanon, Libya, Morocco, Oman, Pakistan, Palestine, Qatar,

4. CRISPR-Cas9-modified <em>pfmdr1</em> protects <em>Plasmodium falciparum </em>asexual blood stages and gametocytes against a class of... (Publications)

   CRISPR-Cas9-modified <em>pfmdr1</em> protects <em>Plasmodium falciparum </em>asexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination therapy partner drugs

   Pertinence:

   Emerging resistance to first-line antimalarial combination therapies threatens malaria treatment and the global elimination campaign. Improved therapeutic strategies are required to protect existing d

5. Antibody-mediated neutralization of the exotoxin mycolactone, the main virulence factor produced by <em>Mycobacterium ulcerans</em> (Publications)

   Antibody-mediated neutralization of the exotoxin mycolactone, the main virulence factor produced by <em>Mycobacterium ulcerans</em>

   Pertinence:

   BACKGROUND: Mycolactone, the macrolide exotoxin produced by Mycobacterium ulcerans, causes extensive tissue destruction by inducing apoptosis of host cells. In this study, we aimed at the production o

6. Non-vector-borne transmission of Zika virus: a systematic review (Publications)

   Non-vector-borne transmission of Zika virus: a systematic review

   Pertinence:

   BACKGROUND: Increasing numbers of confirmed cases of Zika virus (ZIKV) infection resulting from non-mosquito-borne transmission have been reported. METHODS: We performed a systematic literature review

7. Evaluation of malaria diagnoses using a handheld light microscope in a community-based setting in rural Côte d'Ivoire (Publications)

   Evaluation of malaria diagnoses using a handheld light microscope in a community-based setting in rural Côte d'Ivoire

   Pertinence:

   Portable microscopy may facilitate quality diagnostic care in resource-constrained settings. We compared a handheld light microscope (Newton Nm1) with a mobile phone attachment to conventional light m

8. Comparison of sensitivity and faecal egg counts of mini-FLOTAC using fixed stool samples and Kato-Katz technique for the diagnosis of <em>Schistosoma... (Publications)

   Comparison of sensitivity and faecal egg counts of mini-FLOTAC using fixed stool samples and Kato-Katz technique for the diagnosis of <em>Schistosoma mansoni</em> and soil-transmitted helminths

   Pertinence:

   Accurate diagnostic tools for human helminthiasis are crucial for improved patient management and evaluation of community-based intervention studies. However, the diagnosis of intestinal schistosomias

9. Regular family breakfast was associated with children's overweight and parental education: results from the ENERGY cross-sectional study (Publications)

   Regular family breakfast was associated with children's overweight and parental education: results from the ENERGY cross-sectional study

   Pertinence:

   INTRODUCTION: This study aims to assess (i) the prevalence of having regular family breakfast, lunch, dinner (i.e. 5-7days/week together with their family) among 10-12year olds in Europe, (ii) the ass

10. Discovery and characterization of ACT-451840: an antimalarial drug with a novel mechanism of action (Publications)

    Discovery and characterization of ACT-451840: an antimalarial drug with a novel mechanism of action

    Pertinence:

    More than 40 % of the world's population is at risk of being infected with malaria. Most malaria cases occur in the countries of sub-Saharan Africa, Central and South America, and Asia. Resistance to