Asthma and the menopause: a systematic review and meta-analysis (Publications)
OBJECTIVE: To review the available literature to determine whether the menopausal transition is associated with asthma incidence.METHODS: We performed a systematic review and meta-analysis of cohort a
alpha1-Antitrypsin deficiency and lung disease: risk modification by occupational and environmental inhalants (Publications)
Chronic obstructive pulmonary disease (COPD) is a prevalent and preventable disease associated with high morbidity and mortality. Severe and intermediate alpha1-antitrypsin (AAT) deficiency (serum lev
IgE levels, atopy markers and hay fever in relation to age, sex and smoking status in a normal adult Swiss population (Publications)
Within the framework of the SAPALDIA survey (Swiss study on Air Pollution and Lung Diseases in Adults), we studied the influence of sex, age and smoking habits on total serum IgE and allergen-specific
Long-term ambient air pollution and respiratory symptoms in adults (SAPALDIA study) (Publications)
The association between long-term exposure to ambient air pollution and respiratory symptoms was investigated in a cross-sectional study in random population samples of adults (aged 18 to 60 yr, n = 9
Glutathione S-transferase polymorphisms, passive smoking, obesity, and heart rate variability in nonsmokers (Publications)
BACKGROUND: Disturbances of heart rate variability (HRV) may represent one pathway by which second-hand smoke (SHS) and air pollutants affect cardiovascular morbidity and mortality. The mechanisms are
Ten-year follow-up of cluster-based asthma phenotypes in adults: a pooled analysis of three cohorts (Publications)
Rationale: The temporal stability of adult asthma phenotypes identified using clustering methods has never been addressed. Longitudinal cluster-based methods may provide novel insights in the study of
Clinical diagnosis of current asthma: predictive value of respiratory symptoms in the SAPALDIA study. Swiss Study on Air Pollution and Lung Diseases... (Publications)
Bronchial asthma is a very common disease which often remains underdiagnosed. The aim of this study was to determine the predictive value of the most common respiratory symptoms and to explore the bes
Effects of filter choice in GT3X accelerometer assessments of free-living activity (Publications)
PURPOSE: Actigraph accelerometers are widely used devices to objectively assess physical activity. The GT3X version has two filter options to be selected prior to data assessment (normal and low frequ
Predictors of methacholine responsiveness in a general population (Publications)
OBJECTIVE: Methacholine responsiveness is an end point widely used in epidemiologic studies of asthma. This study aims to quantify the relative importance of different predictors of responsiveness suc
