Modification of the association between PM10 and lung function decline by cadherin 13 polymorphisms in the SAPALDIA cohort: a genome-wide interaction... (Publications)
Background: Both air pollution and genetic variation have been shown to affect lung function. Their interaction has not been studied on a genome-wide scale to date. Objectives: We aimed to identify, i
Long-term exposure to traffic-related PM10 and decreased heart rate variability: is the association restricted to subjects taking ACE inhibitors? (Publications)
BACKGROUND: Alterations in heart rate variability (HRV) are a potential link between exposure to traffic-related air pollution and cardiovascular mortality. OBJECTIVES: We investigated whether long-te
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis (Publications)
Atopic dermatitis (AD) is a commonly occurring chronic skin disease with high heritability. Apart from filaggrin (FLG), the genes influencing atopic dermatitis are largely unknown. We conducted a geno
Genome-wide association and functional follow-up reveals new loci for kidney function (Publications)
Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide association studies in up to 130,600 European ancestry participants overall, and s
Long-term exposure to elemental constituents of particulate matter and cardiovascular mortality in 19 European cohorts: Results from the ESCAPE and... (Publications)
BACKGROUND: Associations between long-term exposure to ambient particulate matter (PM) and cardiovascular (CVD) mortality have been widely recognized. However, health effects of long-term exposure to
Association between ambient air pollution and diabetes mellitus in Europe and North America: systematic review and meta-analysis (Publications)
BACKGROUND: Air pollution is hypothesized to be a risk factor for diabetes. Epidemiological evidence is inconsistent and has not been systematically evaluated. OBJECTIVES: We systematically reviewed e
Air pollution from road traffic and systemic inflammation in adults: a cross-sectional analysis in the European ESCAPE project (Publications)
BACKGROUND: Exposure to particulate matter air pollution (PM) has been associated with cardiovascular diseases. OBJECTIVES: This study evaluated whether annual exposure to ambient air pollution is ass
Ambient air pollution and adult asthma incidence in six European cohorts (ESCAPE) (Publications)
BACKGROUND: Short-term exposure to air pollution has adverse effects among patients with asthma, but whether long-term exposure to air pollution is a cause of adult-onset asthma is unclear. OBJECTIVE:
