Investigation of acyclic uridine amide and 5'-amido nucleoside analogues as potential inhibitors of the <em>Plasmodium falciparum</em> dUTPase (Publications)
Previously we have shown that trityl and diphenyl deoxyuridine derivatives and their acyclic analogues can inhibit Plasmodium falciparum dUTPase (PfdUTPase). We report the synthesis of conformationall
High throughput multiplex assay for species identification of Papua New Guinea malaria vectors: members of the <em>Anopheles punctulatus</em>... (Publications)
Malaria and filariasis are transmitted in the Southwest Pacific region by Anopheles punctulatus sibling species including An. punctulatus, An. koliensis, the An. farauti complex 1-8 (includes An. hine
Structure-activity relationship studies of pyrrolone antimalarial agents (Publications)
Previously reported pyrrolones, such as TDR32570, exhibited potential as antimalarial agents; however, while these compounds have potent antimalarial activity, they suffer from poor aqueous solubility
Sociocultural determinants of anticipated vaccine acceptance for acute watery diarrhea in early childhood in Katanga province, Democratic Republic of... (Publications)
Rotavirus and oral cholera vaccines have the potential to reduce diarrhea-related child mortality in low-income settings and are recommended by the World Health Organization. Uptake of vaccination dep
Health of mobile pastoralists in the Sahel - assessment of 15 years of research and development (Publications)
In the Sahel, between Mauritania and Somalia including Northern Kenya, about 20-30 million people live as mobile pastoralists. The rhythm of their migration follows the seasons and the availability of
Development and back-extrapolation of NO2 land use regression models for historic exposure assessment in Great Britain (Publications)
Modelling historic air pollution exposures is often restricted by availability of monitored concentration data. We evaluated back-extrapolation of LUR models for annual mean NO2 concentrations in Grea
Treatment of mucosal leishmaniasis (<em>L. infantum</em>) with Miltefosine in a patient with good syndrome (Publications)
We report on a 76-year old patient with recurrent mucosal leishmaniasis. Multiple treatment regimens were administered. After the second relapse, immunologic workup and review of the patient's history
Household survey of pesticide practice, deliberate self-harm and suicide in the Sundarban region of west Bengal, India (Publications)
The toxicological impact and intentional ingestion of pesticides are major public health concerns globally. This study aimed to estimate the extent of deliberate self-harm (DSH) and suicides (suicidal
