Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks... (Publications)
BACKGROUND: The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) is the first of a series of annual updates of the GBD. Risk factor quantification, particularly of modifiable
Vaccination with the surface proteins MUL_2232 and MUL_3720 of <em>Mycobacterium ulcerans</em> induces antibodies but fails to provide protection... (Publications)
BACKGROUND: Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a chronic ulcerative neglected tropical disease of the skin and subcutaneous tissue that is most prevalent in West African
Interferon-gamma is a crucial activator of early host immune defense against <em>Mycobacterium ulcerans</em> infection in mice (Publications)
Buruli ulcer (BU), caused by infection with Mycobacterium ulcerans, is a chronic necrotizing human skin disease associated with the production of the cytotoxic macrolide exotoxin mycolactone. Despite
Isolation of nontuberculous <em>Mycobacteria</em> from the environment of Buruli ulcer endemic communities in Ghana (Publications)
BACKGROUND: This study aimed to isolate nontuberculous mycobacterial species from environmental samples obtained from some selected communities in Ghana. METHODS: To optimise decontamination, spiked e
Multilevel analysis of childbearing in childhood in Tanzania's Rufiji district (Publications)
Objectives To examine levels, trends and correlates of childbearing in childhood (CiC) in the Rufiji district of Tanzania from 2002 to 2010. Methods Using longitudinal data collected in, and by, the R
Assessment of global guidelines for preventive chemotherapy against schistosomiasis and soil-transmitted helminthiasis: a cost-effectiveness modelling... (Publications)
BACKGROUND: WHO guidelines recommend annual treatment for schistosomiasis or soil-transmitted helminthiasis when prevalence in school-aged children is at or above a threshold of 50% and 20%, respectiv
Spatially variable risk factors for malaria in a geographically heterogeneous landscape, western Kenya: an explorative study (Publications)
BACKGROUND: Large reductions in malaria transmission and mortality have been achieved over the last decade, and this has mainly been attributed to the scale-up of long-lasting insecticidal bed nets an
Comparative genomics of drug resistance in<em> Trypanosoma brucei</em> rhodesiense (Publications)
Trypanosoma brucei rhodesiense is one of the causative agents of human sleeping sickness, a fatal disease that is transmitted by tsetse flies and restricted to Sub-Saharan Africa. Here we investigate
