Mortality of neurological disorders in Tanzania: analysis of baseline data from sample vital registration with verbal autopsy (SAVVY) (Publications)
Background: Neurological disorders (ND) have a profound consequence on human productivity, quality of life and survival. There are limited data on the burden of ND in Tanzania due to insufficient cove
Genetic risk scores do not improve asthma prediction in childhood (Publications)
CAPSULE SUMMARY: Genetic risk scores have no added value above familial, perinatal and environmental risk factors in the first year of life to predict childhood asthma.
Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies (Publications)
INTRODUCTION: Novel cancer therapies are often approved with evidence from a single pivotal trial alone. There are concerns about the credibility of this evidence. Higher validity may be indicated by
RTS,S malaria vaccine pilot studies: addressing the human realities in large-scale clinical trials (Publications)
A malaria vaccine as part of the integrated malaria control and elimination efforts will have a major impact on public health in sub-Sahara Africa. The first malaria vaccine, RTS,S, now enters pilot i
Linking human behaviours and malaria vector biting risk in south-eastern Tanzania (Publications)
To accelerate malaria elimination in areas where core interventions such as insecticide-treated nets (ITNs) are already widely used, it is crucial to consider additional factors associated with persis
The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes (Publications)
The generation of protective humoral immunity after vaccination relies on the productive interaction between antigen-specific B cells and T follicular helper (Tfh) cells. Despite the central role of T
