Semi-field evaluation of a volatile transfluthrin-based intervention reveals efficacy as a spatial repellent and evidence of other modes of action (Publications)
biting is suspected to contribute to malaria transmission, where people are active in the evening in open-walled outdoor kitchens. This study assessed the VPSR in replica kitchens within a controlled semi-field
Modelling the impact of Omicron and emerging variants on SARS-CoV-2 transmission and public health burden (Publications)
guiding ongoing COVID-19 control strategies. Methods: With an individual-based transmission model, OpenCOVID, we simulated three viral properties; infectivity, severity, and immune-evading ability, all
Framework synthesis to inform the ideation and design of a paper-based health information system (PHISICC) (Publications)
Register of Controlled Trials (CENTRAL), Embase, Epistemonikos, Medline, in-Process on the Ovid platform, OpenGrey, PDQ Evidence ("pretty darnd quick" Evidence), the World Health Organization (WHO) Global Health
Non-Markovian modelling highlights the importance of age structure on Covid-19 epidemiological dynamics (Publications)
study shows the flexibility and robustness of PDE formalism to capture national COVID-19 dynamics and opens perspectives to study medium or long-term scenarios involving immune waning or virus evolution.
SARS-CoV-2 variants of concern in children and adolescents with COVID-19: a systematic review (Publications)
long-term consequences following a VOC infection. DESIGN: Systematic review. DATA SOURCES: The COVID-19 Open Access Project database was searched up to 1 March 2022 and PubMed was searched up to 9 May 2022.
Whole genome sequencing distinguishes between relapse and reinfection in recurrent leprosy cases (Publications)
enrichment methods from samples from three recurrent cases in leprosy patients participating in an open-label, randomized, controlled clinical trial of uniform MDT in Brazil (U-MDT/CT-BR). Genome-wide
AnophelesModel: an R package to interface mosquito bionomics, human exposure and intervention effects with models of malaria intervention impact (Publications)
available for different geographical regions, we developed AnophelesModel. AnophelesModel is an online, open-access R package that quantifies the impact of vector control interventions depending on mosquito
Epidemiology and Viral Evolution | Research at Swiss TPH (Page)
https://www.swisstph.ch/fr/about/mpi/epidemiology-and-viral-evolution
insights into the ever-evolving 'dance' between viruses and humans. Pathoplexus Pathoplexus is a new, open-source database dedicated to the efficient sharing of human viral pathogen genomic data, fostering [...] looking at factors like reinfection, waning immunity, and immune pressure on viral epitopes. Using an open-source resource on Nextstrain, the research will facilitate real-time tracking of NP-EV evolution
Implementation of a Digital Clinical Decision Support System / ICRC Libya (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/implementation-of-a-digital-clinical-decision-support-system-/-icrc-libya
health outcomes had been proven in a large-scale scientific evaluation (Schmitz T, Beynon F et al. BMJ Open 2022; doi:10.1136/bmjopen-2021-055315). In 2021, ICRC decided to replicate the ALMANACH project for [...] Ministry of Health Development of the ICT code to transcribe the clinical content to be processed by an open-source software called Community Health Toolkit (CHT) Elaboration of training material and facilitation
Oral fexinidazole for late-stage African <em>Trypanosoma brucei gambiense </em>trypanosomiasis: a pivotal multicentre, randomised, non-inferiority... (Publications)
ne combination therapy in patients with late-stage g-HAT. METHODS: In this randomised, phase 2/3, open-label, non-inferiority trial, we recruited patients aged 15 years and older with late-stage g-HAT
