Cause of death estimation from verbal autopsies: is the open response redundant or synergistic? (Publications)
of the deceased. The VA includes both Closed Questions (CQs) with structured answer options, and an Open Response (OR) consisting of a free narrative of the events expressed in natural language and without
Resistance-informed versus empirical management of viraemia in children and adolescents with HIV in Lesotho and Tanzania (GIVE MOVE trial): a... (Publications)
little access to GRT. METHODS: The Genotype-Informed Versus Empirical Management of Viremia (GIVE MOVE) open-label, parallel-group randomised controlled trial enrolled children and adolescents with HIV between
The quality of OpenStreetMap food-related point-of-interest data for use in epidemiological research (Publications)
We assessed the quality of food-related OpenStreetMap (OSM) data in urban areas of five European countries. We calculated agreement statistics between point-of-interests (POIs) from OSM and from Google
Efficacy and safety of acoziborole in patients with human African trypanosomiasis caused by <em>Trypanosoma brucei gambiense</em>: a multicentre,... (Publications)
acoziborole in adult and adolescent patients with gambiense HAT. Methods This multicentre, prospective, open-label, single-arm, phase 2/3 study recruited patients aged 15 years or older with confirmed gambiense
Efficacy, safety, and palatability of arpraziquantel (L-praziquantel) orodispersible tablets in children aged 3 months to 6 years infected with... (Publications)
arpraziquantel (L-praziquantel) orodispersible tablets for preschool-aged children. METHODS: This open-label, partly randomised, phase 3 study was conducted at two hospitals in Cote d'Ivoire and Kenya
Local heat application for the treatment of Buruli ulcer: results of a phase II open label single center non comparative clinical trial (Publications)
efficacy of a local heat application device based on phase change material. METHODS: In a phase II open label single center non comparative clinical trial (ISRCTN 72102977) under GCP standards in Cameroon
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond (Publications)
industry. Open source drug discovery, with sharing of information, is clearly a first step towards overcoming this gap. But the interface could especially be bridged through a scale-up of open sharing of [...] expertise in biological assays involving human pathogens into drug discovery starting points, by providing open access to new families of molecules, and emphasize how a small additional investment made to help
Open source drug discovery: highly potent antimalarial compounds derived from the Tres Cantos arylpyrroles (Publications)
potential starting points for hit-to-lead campaigns. One such public set is explored, employing an open source research mechanism in which all data and ideas were shared in real time, anyone was able to [...] including activity within gametocyte and liver stage assays, but at the cost of low solubility. As an open source research project, unexplored avenues are clearly identified and may be explored further by
Managing research and surveillance projects in real-time with a novel open-source eManagement tool designed for under-resourced countries (Publications)
is lightweight and uses minimal internet resources. It was designed to be used with the open source software Open Data Kit (ODK). The users can easily configure odk_planner to meet their needs, and the [...] tracked sputum samples, and collected clinical and laboratory data. CONCLUSIONS: The user friendly, open source odk_planner is a simple, but multi-functional, Web-based eManagement tool with add-ons that
