Deletion in the gene BruAb2_0168 of <em>Brucella abortus</em> strains: diagnostic challenges (Publications)
Three Brucella abortus strains were isolated from joint hygromas from cows in northern Togo. Two deletions in the 5' side of the gene BruAb2_0168 were identified. As this gene is used for species iden
PolyTB: a genomic variation map for <em>Mycobacterium tuberculosis</em> (Publications)
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is the second major cause of death from an infectious disease worldwide. Recent advances in DNA sequencing are leading to the ability to ge
Differences in conformational dynamics between <em>Plasmodium falciparum</em> and human Hsp90 orthologues enable the structure-based discovery of... (Publications)
The high sequence conservation of druggable pockets of closely related proteins can make it challenging to develop selective inhibitors. We designed a new drug discovery approach that exploits both th
Atopic conditions and brain tumor risk in children and adolescents: an international case-control study (CEFALO) (Publications)
BACKGROUND: A number of epidemiological studies indicate an inverse association between atopy and brain tumors in adults, particularly gliomas. We investigated the association between atopic disorders
A profile of travelers - an analysis from a large Swiss travel clinic (Publications)
BACKGROUND: Globally, the Swiss have one of the highest proportions of the population traveling to tropical and subtropical countries. Large travel clinics serve an increasing number of customers with
Paraspinal abscess secondary to tuberculous spondylitis diagnosed by Xpert MTB/RIF assay in rural Tanzania (Publications)
A 31-year-old HIV-negative man presented to our clinic with a 6-month history of back pain and a swelling at the back. Radiological studies revealed lumbar vertebral destruction. Ultrasound of the mas
Evidence for diversifying selection in a set of <em>Mycobacterium tuberculosis</em> genes in response to antibiotic- and nonantibiotic-related... (Publications)
Tuberculosis (TB) is a global health problem estimated to kill 1.4 million people per year. Recent advances in the genomics of the causative agents of TB, bacteria known as the Mycobacterium tuberculo
Epidemiology of malaria in the Papua New Guinean highlands (Publications)
Objectives To conduct an in-depth investigation of the epidemiology of malaria in the Papua New Guinea (PNG) highlands and provide a basis for evidence-based planning and monitoring of intensified mal