Recherche de open.

1. Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, tribendimidine, and praziquantel in patients with <em>Opisthorchis... (Publications)

   Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, tribendimidine, and praziquantel in patients with <em>Opisthorchis viverrini</em>: a randomised, exploratory, open-label, phase 2 trial

   Pertinence:

   compared with that of praziquantel in patients with O viverrini infection. METHODS: We did a randomised open-label trial between February and April, 2010, in the Saysetha district, Attapeu Province, Laos. Eligible

2. A prospective, open-label, randomized trial of doxycycline versus azithromycin for the treatment of uncomplicated murine typhus (Publications)

   A prospective, open-label, randomized trial of doxycycline versus azithromycin for the treatment of uncomplicated murine typhus

   Pertinence:

   evidence for optimum treatment duration. Azithromycin is a potential alternative. Methods: A prospective, open, randomised trial was conducted in non-pregnant, consenting inpatient adults with rapid diagnostic

3. Efficacy of single versus four repeated doses of praziquantel agains<em>t Schistosoma mansoni </em>infection in school-aged children from Côte... (Publications)

   Efficacy of single versus four repeated doses of praziquantel agains<em>t Schistosoma mansoni </em>infection in school-aged children from Côte d'Ivoire based on Kato-Katz and POC-CCA: an open-label, randomised controlled trial (RePST)

   Pertinence:

   infection in school-aged children from Cote d'Ivoire, using two different diagnostic tests. METHODS: An open-label, randomized controlled trial was conducted from October 2018 to January 2019. School-aged children

4. OpenHDS: Use of tablet computers in health and demographic surveillance (Publications)

   OpenHDS: Use of tablet computers in health and demographic surveillance

   Pertinence:

5. Microbial contamination along the main open wastewater and storm water channel of Hanoi, Vietnam, and potential health risks for urban farmers (Publications)

   Microbial contamination along the main open wastewater and storm water channel of Hanoi, Vietnam, and potential health risks for urban farmers

   Pertinence:

   The use of wastewater in agriculture and aquaculture has a long tradition throughout Asia. For example, in Hanoi, it creates important livelihood opportunities for > 500,000 farmers in peri-urban comm

6. A multicenter, open label, phase III study of therapeutic use of the co-administration of nifurtimox and eflornithine (NECT) for human African... (Publications)

   A multicenter, open label, phase III study of therapeutic use of the co-administration of nifurtimox and eflornithine (NECT) for human African trypanosomiasis (NECT field): safety profile in children during initial hospitalization

   Pertinence:

7. In Tanzania, the many costs of pay-for-performance leave open to debate whether the strategy is cost-effective (Publications)

   In Tanzania, the many costs of pay-for-performance leave open to debate whether the strategy is cost-effective

   Pertinence:

   Pay-for-performance programs in health care are widespread in low- and middle-income countries. However, there are no studies of these programs' costs or cost-effectiveness. We conducted a cost-effect

8. Development of an open-source road traffic noise model for exposure assessment (Publications)

   Development of an open-source road traffic noise model for exposure assessment

   Pertinence:

9. Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis... (Publications)

   Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis treatment: a phase 2b, open-label, partly randomised trial in patients with drug-susceptible or drug-resistant pul

   Pertinence:

   BACKGROUND: New antituberculosis regimens are urgently needed to shorten tuberculosis treatment. Following on from favourable assessment in a 2 week study, we investigated a novel regimen for efficacy

10. Repurposing of the open access malaria box for kinetoplastid diseases identifies novel active scaffolds against trypanosomatids (Publications)

    Repurposing of the open access malaria box for kinetoplastid diseases identifies novel active scaffolds against trypanosomatids

    Pertinence:

    Phenotypic screening had successfully been used for hit generation, especially in the field of neglected diseases, in which feeding the drug pipeline with new chemotypes remains a constant challenge.