Structure-activity relationship studies of orally active antimalarial 2,4-diamino-thienopyrimidines (Publications)
Based on the initial optimization of orally active antimalarial 2,4-diamino-thienopyrimidines and with the help of metabolite identification studies, a second generation of derivatives involving chang
Indoloditerpenes from a marine-derived fungal strain of <em>Dichotomomyces cejpii</em> with antagonistic activity at GPR18 and cannabinoid receptors (Publications)
A marine-derived strain of Dichotomomyces cejpii produces the new compounds emindole SB beta-mannoside (1) and 27-O-methylasporyzin C (2), as well as the known indoloditerpenes JBIR-03 (3) and emindol
Near-roadway air pollution and coronary heart disease: burden of disease and potential impact of a greenhouse gas reduction strategy in southern... (Publications)
BACKGROUND: Several studies have estimated the burden of coronary heart disease (CHD) mortality from ambient regional particulate matter
Transmission of <em>Opisthorchis viverrini, Schistosoma mekongi </em>and soil-transmitted helminths on the Mekong Islands, southern Lao PDR (Publications)
BACKGROUND: Prevalence of Opisthorchis viverrini, Schistosoma mekongi and soil-transmitted helminths (STH) remains high in Lao People's Democratic Republic (Lao PDR), despite control efforts including
Previous exposure in a high-risk area for travellers' diarrhoea within the past year is associated with a significant protective effect for... (Publications)
Background: Travellers' diarrhoea is the most common health problem in travellers. Depending on the region visited, up to 40% of travellers develop diarrhoea during a 2-week trip. The aim of this stud
Cancer predisposition cascade screening for hereditary breast/ovarian cancer and lynch syndromes in Switzerland: study protocol (Publications)
BACKGROUND: Breast, colorectal, ovarian, and endometrial cancers constitute approximately 30% of newly diagnosed cancer cases in Switzerland, affecting more than 12,000 individuals annually. Hundreds
Ferrocenyl, ruthenocenyl, and benzyl oxamniquine derivatives with cross-species activity against <em>Schistosoma mansoni </em>and <em>Schistosoma... (Publications)
Schistosomiasis is a parasitic disease that affects more than 250 million people annually, mostly children in poor, tropical, rural areas. Only one treatment (praziquantel) is available, putting contr
School children's intestinal parasite and nutritional status 1 year after complementary school garden, nutrition, water, sanitation, and hygiene... (Publications)
The potential health benefits of combined agricultural, nutrition, water, sanitation, and hygiene (WASH) interventions are poorly understood. We aimed to determine whether complementary school garden,