Publications
Wyss M, Kanyal A, Niederwieser I, Bartfai R, Voss T.S. The Plasmodium falciparum histone methyltransferase PfSET10 is dispensable for the regulation of antigenic variation and gene expression in blood-stage parasites. mSphere. 2024(in press). DOI: 10.1128/msphere.00546-24
Tibúrcio M, Hitz E, Niederwieser I, Kelly G, Davies H, Doerig C, Billker O, Voss T.S, Treeck M. A 39-amino-acid C-terminal truncation of GDV1 disrupts sexual commitment in Plasmodium falciparum. mSphere. 2021;6(3):e01093-20. DOI: 10.1128/mSphere.01093-20
Bui H.T.N, Niederwieser I, Bird M.J, Dai W, Brancucci N.M.B, Moes S, Jenoe P, Lucet I.S, Doerig C, Voss T.S. Mapping and functional analysis of heterochromatin protein 1 phosphorylation in the malaria parasite Plasmodium falciparum. Sci Rep. 2019;9:16720. DOI: 10.1038/s41598-019-53325-9
Filarsky M, Fraschka S.A, Niederwieser I, Brancucci N.M.B, Carrington E, Carrió E, Moes S, Jenoe P, Bartfai R, Voss T.S. GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencing. Science. 2018;359(6381):1259-1263. DOI: 10.1126/science.aan6042
Fraschka S.A, Filarsky M, Hoo R, Niederwieser I, Yan Yam X, Brancucci N.M.B, Mohring F, Mushunje A.T, Huang X, Christensen P.R, Nosten F, Bozdech Z, Russell B, Moon R.W, Marti M, Preiser P.R, Bártfai R, Voss T.S. Comparative heterochromatin profiling reveals conserved and unique epigenome signatures linked to adaptation and development of malaria parasites. Cell Host Microbe. 2018;23(3):407-420 e8. DOI: 10.1016/j.chom.2018.01.008
Bertschi N.L, Toenhake C.G, Zou A, Niederwieser I, Henderson R, Moes S, Jenoe P, Parkinson J, Bartfai R, Voss T.S. Malaria parasites possess a telomere repeat-binding protein that shares ancestry with transcription factor IIIA. Nat Microbiol. 2017;2:17033. DOI: 10.1038/nmicrobiol.2017.33
Brancucci N.M.B, Gerdt J.P, Wang C, De Niz M, Philip N, Adapa S.R, Zhang M, Hitz E, Niederwieser I, Boltryk S.D, Laffitte M.C, Clark M.A, Gruring C, Ravel D, Blancke Soares A, Demas A, Bopp S, Rubio-Ruiz B, Conejo-Garcia A, Wirth D.F, Gendaszewska-Darmach E, Duraisingh M.T, Adams J.H, Voss T.S, Waters A.P, Jiang R.H.Y, Clardy J, Marti M. Lysophosphatidylcholine regulates sexual stage differentiation in the human malaria parasite Plasmodium falciparum. Cell. 2017;171(7):1532-1544 e15. DOI: 10.1016/j.cell.2017.10.020
Brancucci N.M, Bertschi N.L, Zhu L, Niederwieser I, Chin W.H, Wampfler R, Freymond C, Rottmann M, Felger I, Bozdech Z, Voss T.S. Heterochromatin protein 1 secures survival and transmission of malaria parasites. Cell Host Microbe. 2014;16(2):165-176. DOI: 10.1016/j.chom.2014.07.004
Oehring S.C, Woodcroft B.J, Moes S, Wetzel J, Dietz O, Pulfer A, Dekiwadia C, Mäser P, Flück C, Witmer K, Brancucci N.M, Niederwieser I, Jenoe P, Ralph S.A, Voss T.S. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Genome Biol. 2012;13(11):R108. DOI: 10.1186/gb-2012-13-11-r108
Flueck C, Bartfai R, Niederwieser I, Witmer K, Alako B.T, Moes S, Bozdech Z, Jenoe P, Stunnenberg H.G, Voss T.S. A major role for the Plasmodium falciparum ApiAP2 protein PfSIP2 in chromosome end biology. PLoS Pathog. 2010;6(2):e1000784. DOI: 10.1371/journal.ppat.1000784
Flueck C, Bartfai R, Volz J, Niederwieser I, Salcedo-Amaya A.M, Alako B.T, Ehlgen F, Ralph S.A, Cowman A.F, Bozdech Z, Stunnenberg H.G, Voss T.S. Plasmodium falciparum heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors. PLoS Pathog. 2009;5(9):e1000569. DOI: 10.1371/journal.ppat.1000569
Niederwieser Igor. Leishmania infantum: molecular analysis for identification of potential virulence factors and genes of diagnostic use. Basel: Univ. Basel, 2004. Doctoral Thesis, University of Basel, Faculty of Science DOI: 10.5451/unibas-003984051
Thesis
Marfurt J, Nasereddin A, Niederwieser I, Jaffe C.L, Beck H.P, Felger I. Identification and differentiation of Leishmania species in clinical samples by PCR amplification of the miniexon sequence and subsequent restriction fragment length polymorphism analysis. J Clin Microbiol. 2003;41(7):3147-3153
Marfurt J, Niederwieser I, Makia D, Beck H.P, Felger I. Diagnostic genotyping of old and new world Leishmania species by PCR-RFLP. Diagn Microbiol Infect Dis. 2003;46(2):115-124
Niederwieser I, Felger I, Beck H.P. Limited polymorphism in Plasmodium falciparum sexual-stage antigens. Am J Trop Med Hyg. 2001;64(1-2):9-11
Niederwieser I, Felger I, Beck H.P. Plasmodium falciparum: expression of gametocyte specific genes in monolayer cultures and malaria positive blood samples. Exp Parasitol. 2000;95(3):163-169