Publications

Nickel B, Krebs C, Ruf M.T, Anuar N.S, Noordin R. An evaluation of a lateral flow rapid diagnostic test for Strongyloides stercoralis infection. Acta Trop. 2024;258:107336. DOI: 10.1016/j.actatropica.2024.107336

Coste A.T, Egli A, Schrenzel J, Nickel B, Zbinden A, Lienhard R, Dumoulin A, Risch M, Greub G. IVDR: analysis of the social, economic, and practical consequences of the application of an ordinance of the in vitro diagnostic ordinance in Switzerland. Diagnostics (Basel). 2023;13(18):2910. DOI: 10.3390/diagnostics13182910

Edridge A.W.D, Abd-Elfarag G, Deijs M, Broeks M.H, Cristella C, Sie B, Vaz F.M, Jans J.J.M, Calis J, Verhoef H, Demir A, Poppert S, Nickel B, van Dam A, Sebit B, Titulaer M.J, Verweij J.J, de Jong M.D, van Gool T, Faragher B, Verhoeven-Duif N.M, Elledge S.J, van der Hoek L, Boele van Hensbroek M. Parasitic, bacterial, viral, immune-mediated, metabolic and nutritional factors associated with nodding syndrome. Brain Commun. 2023;5(5):fcad223. DOI: 10.1093/braincomms/fcad223

Stürmann Anna, Endriss Yvette, Nickel Beatrice, Odermatt Peter, Pelikan Joachim. Introduction to diagnostic medical parasitology. Basel: Swiss Tropical and Public Health Institute, 2023. This learning software allows beginners to gain experience in diagnosing the most important helminth and protozoan infections of humans. For this purpose, one can gain basic knowledge through short overviews of parasites, diseases, diagnostic methods and strategies. Even more important, one can train diagnostic capabilities using a virtual microscope. The course leads the student from basic training to more complicated diagnostic exercises. Our purpose is to facilitate a first approach to Diagnostic Medical Parasitology. This programme cannot replace working with a real microscope or consulting diagnostic textbooks and atlases.

Bapat A, Nickel B, Bray T.J.P, Abbasi M, Stone N.R.H. Case report: gnathostomiasis acquired in Costa Rica in a returning traveler to the United Kingdom. Am J Trop Med Hyg. 2022;106(4):1263–1264. DOI: 10.4269/ajtmh.21-1215

Hoekstra P.T, Chernet A, de Dood C.J, Brienen E.A.T, Corstjens P.L.A.M, Labhardt N.D, Nickel B, Wammes L, van Dam G.J, Neumayr A, van Lieshout L. Sensitive diagnosis and post-treatment follow-up of Schistosoma mansoni infections in asymptomatic Eritrean refugees by Circulating Anodic Antigen (CAA) detection and PCR. Am J Trop Med Hyg. 2022;106(4):1240-1246. DOI: 10.4269/ajtmh.21-0803

Hörmann J, Kuenzli E, Schaefer C, Paris D.H, Bühler S, Odermatt P, Sayasone S, Neumayr A, Nickel B. Performance of a rapid immuno-chromatographic test (Schistosoma ICT IgG-IgM) for detecting Schistosoma-specific antibodies in sera of endemic and non-endemic populations. PLoS Negl Trop Dis. 2022;16(5):e0010463. DOI: 10.1371/journal.pntd.0010463

Carnino L, Schwob J.M, Gétaz L, Nickel B, Neumayr A, Eperon G. A practical approach to screening for Strongyloides stercoralis. Trop Med Infect Dis. 2021;6(4):203. DOI: 10.3390/tropicalmed6040203

Frickmann H, Loderstädt U, Nickel B, Poppert S, Odermatt P, Sayasone S, Van Esbroeck M, Micalessi I, Cnops L, Adisakwattana P, Leboulle G, Landt O, Thye T, Tannich E. Low sensitivity of real time PCRs targeting retrotransposon sequences for the detection of Schistosoma japonicum complex DNA in human serum. Pathogens. 2021;10(8):1067. DOI: 10.3390/pathogens10081067

Niederhauser C, Tinguely C, Dreier J, Vollmer T, Marti H, Nickel B, Klemens J.M, Warnecke J.M, Gowland P. Comparison of a new IgG-EIA for the detection of anti-plasmodium antibodies with two currently used assays. Transfus Med Hemother. 2021;48(5):265-271. DOI: 10.1159/000515842

Roure S, Fernández-Rivas G, Ruf M.T, Grau-López L, Guarro L, Matas L, Nickel B, Valerio L. A cluster of travelers with headache and a hidden travel companion, Angiostrongylus cantonensis: a diagnostic challenge. Travel Med Infect Dis. 2021;44:102187. DOI: 10.1016/j.tmaid.2021.102187

Tanida K, Balczun C, Hahn A, Veit A, Nickel B, Poppert S, Scheid P.L, Hagen R.M, Frickmann H, Loderstädt U, Tannich E. Comparison of three in-house real PCR assays targeting kinetoplast DNA, the small subunit ribosomal RNA gene and the glucose-6-phosphate isomerase gene for the detection of Leishmania spp. in human serum. Pathogens. 2021;10(7):826. DOI: 10.3390/pathogens10070826

Chankongsin S, Wampfler R, Ruf M.T, Odermatt P, Marti H, Nickel B, Keoluangkhot V, Neumayr A. Strongyloides stercoralis prevalence and diagnostics in Vientiane, Lao People's Democratic Republic. Infect Dis Poverty. 2020;9:133. DOI: 10.1186/s40249-020-00750-y

Marti H, Halbeisen S, Bausch K, Nickel B, Neumayr A. Specificity of the POC-CCA urine test for diagnosing S. mansoni schistosomiasis. Travel Med Infect Dis. 2020;33:101473. DOI: 10.1016/j.tmaid.2019.101473

Mudji J, Blum A, Grize L, Wampfler R, Ruf M.T, Cnops L, Nickel B, Burri C, Blum J. Gambiense human African trypanosomiasis sequelae after treatment: a follow-up study 12 years after treatment. Trop Med Infect Dis. 2020;5(1):10. DOI: 10.3390/tropicalmed5010010

Muigg V, Seth-Smith H.M.B, Goldenberger D, Egli A, Nickel B, Durig R, Kuenzli E, Hinic V, Neumayr A. Tick-borne relapsing fever caused by Borrelia persica in traveler to Central Asia, 2019. Emerg Infect Dis. 2020;26(4):824-826. DOI: 10.3201/2604.191771

Noordin R, Khanbabaie S, Hafiznur Yunus M, Marti H, Nickel B, Fasihi Harandi M, Nasibi S. Evaluation of the diagnostic performance of recombinant antigen B1 for detection of cystic echinococcosis using lateral flow dipstick test. Iran J Parasitol. 2020;15(3):290-298. DOI: 10.18502/ijpa.v15i3.4191

Brummaier T, Bertschy S, Arn K, Treumann T, Ruf M.T, Nickel B, Paris D.H, Neumayr A, Blum J. A blind passenger: a rare case of documented seroconversion in an Angiostrongylus cantonensis induced eosinophilic meningitis in a traveler visiting friends and relatives. Trop Dis Travel Med Vaccines. 2019;5:6. DOI: 10.1186/s40794-019-0084-x

Neumayr A, Chernet A, Sydow V, Kling K, Künzli E, Marti H, Paris D.H, Nickel B, Labhardt N.D. Performance of the point-of-care circulating cathodic antigen (POC-CCA) urine cassette test for follow-up after treatment of S. mansoni infection in Eritrean refugees. Travel Med Infect Dis. 2019;28:59-63. DOI: 10.1016/j.tmaid.2018.09.004

Sah R, Gupta N, Chatterji P, Krishan S, Aggarwal M, Sood N, Neupane S, Sah S, Sah R, Poppert S, Ruf M.T, Nickel B, Neumayr A. Case report: paragonimiasis presenting with pericardial tamponade. Am J Trop Med Hyg. 2019;101(1):62-64. DOI: 10.4269/ajtmh.19-0018

Staehelin C, Chernet A, Sydow V, Piso R.J, Suter-Riniker F, Funez S, Nickel B, Paris D.H, Labhardt N.D. Seroprotection rates of vaccine-preventable diseases among newly arrived Eritrean asylum seekers in Switzerland: a cross-sectional study. J Travel Med. 2019;26(6):taz035. DOI: 10.1093/jtm/taz035

Chernet A, Neumayr A, Hatz C, Kling K, Sydow V, Rentsch K, Utzinger J, Probst-Hensch N, Marti H, Nickel B, Labhardt N.D. Spectrum of infectious diseases among newly arrived Eritrean refugees in Switzerland: a cross-sectional study. Int J Public Health. 2018;63(2):233-239. DOI: 10.1007/s00038-017-1034-x

Amelio P, Portevin D, Reither K, Mhimbira F, Mpina M, Tumbo A, Nickel B, Marti H, Knopp S, Ding S, Penn-Nicholson A, Darboe F, Ohmiti K, Scriba T.J, Pantaleo G, Daubenberger C, Perreau M. Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania. PLoS Negl Trop Dis. 2017;11(7):e0005817. DOI: 10.1371/journal.pntd.0005817

Benoit T, Majer S, Nickel B, Traichel B. Schwere Eosinophilie. Swiss Med Forum. 2017;17(8):201-204

Benoit T, Majera S, Nickel B, Traichela B. Eine hierzulande eher ungewöhnliche Ursache! Schwere Eosinophilie. Swiss Med Forum. 2017;17(8):201-204

Chernet A, Hensch N.P, Kling K, Sydow V, Hatz C, Paris D.H, Rentsch K, Nickel B, Neumayr A, Labhardt N.D. Serum 25-hydroxyvitamin D levels and intramuscular vitamin D3 supplementation among Eritrean migrants recently arrived in Switzerland. Swiss Med Wkly. 2017;147:w14568. DOI: 10.4414/smw.2017.14568

Chernet A, Kling K, Sydow V, Künzli E, Hatz C, Utzinger J, van Lieshout L, Marti H, Nickel B, Labhardt N.D, Neumayr A. Accuracy of diagnostic tests for Schistosoma mansoni infection in asymptomatic Eritrean refugees: serology and POC-CCA against stool microscopy. Clin Infect Dis. 2017;65(4):568-574. DOI: 10.1093/cid/cix366

Nguyen Y, Rossi B, Argy N, Baker C, Nickel B, Marti H, Zarrouk V, Houze S, Fantin B, Lefort A. Autochthonous case of eosinophilic meningitis caused by Angiostrongylus cantonensis, France, 2016. Emerg Infect Dis. 2017;23(6):1045-1046. DOI: 10.3201/eid2306.161999

Vonghachack Y, Sayasone S, Khieu V, Bergquist R, van Dam G.J, Hoekstra P.T, Corstjens P.L.A.M, Nickel B, Marti H, Utzinger J, Muth S, Odermatt P. Comparison of novel and standard diagnostic tools for the detection of Schistosoma mekongi infection in Lao People's Democratic Republic and Cambodia. Infect Dis Poverty. 2017;6:127. DOI: 10.1186/s40249-017-0335-x

Ampah K.A, Nickel B, Asare P, Ross A, De-Graft D, Kerber S, Spallek R, Singh M, Pluschke G, Yeboah-Manu D, Röltgen K. A sero-epidemiological approach to explore transmission of Mycobacterium ulcerans. PLoS Negl Trop Dis. 2016;10:e0004387. DOI: 10.1371/journal.pntd.0004387

Boelaert M, NIDIAG Consortium. Clinical research on neglected tropical diseases: challenges and solutions. PLoS Negl Trop Dis. 2016;10(11):e0004853. DOI: 10.1371/journal.pntd.0004853

Cornaglia J, Jean M, Bertrand K, Aumaitre H, Roy M, Nickel B. Gnathostomiasis in Brazil: an emerging disease with a challenging diagnosis. J Travel Med. 2016;24(1):taw074. DOI: 10.1093/jtm/taw074

Neumayr A, Ollague J, Bravo F, Gotuzzo E, Jimenez P, Norton S, Doanh P.N, Nawa Y, Horii Y, Nickel B, Marti H. Cross-reactivity pattern of Asian and American human gnathostomiasis in western blot assays using crude antigens prepared from Gnathostoma spinigerum and Gnathostoma binucleatum third-stage larvae. Am J Trop Med Hyg. 2016;95(2):413-416. DOI: 10.4269/ajtmh.16-0176

Becker S.L, Piraisoody N, Kramme S, Marti H, Silué K.D, Panning M, Nickel B, Kern W.V, Herrmann M, Hatz C.F, N'Goran E.K, Utzinger J, von Müller L. Real-time PCR for detection of Strongyloides stercoralis in human stool samples from Côte d'Ivoire: diagnostic accuracy, inter-laboratory comparison and patterns of hookworm co-infection. Acta Trop. 2015;150:210-217. DOI: 10.1016/j.actatropica.2015.07.019

Nickel B, Sayasone S, Vonghachack Y, Odermatt P, Marti H. Schistosoma mansoni antigen detects Schistosoma mekongi infection. Acta Trop. 2015;141(Pt B):310-314. DOI: 10.1016/j.actatropica.2014.08.001

Nickel B, Ahmarani F, Pittet A, List C, Mäser P, Marti H. Evaluation of synthetic peptides from the K39-sequence for diagnostics of visceral leishmaniasis. Trop Med Int Health, 2013;18(Suppl. 1):138

Daubenberger C.A, Nickel B, Ciatto C, Grütter M.G, Pöltl-Frank F, Rossi L, Siegler U, Robinson J, Kashala O, Patarroyo M, Pluschke G. Amino acid dimorphism and parasite immune evasion: cellular immune responses to a promiscuous epitope of Plasmodium falciparum merozoite surface protein 1 displaying dimorphic amino acid polymorphism are highly constrained. Eur J Immunol. 2002;32(12):3667-3677

Kashala O, Amador R, Valero V.M, Moreno A, Barbosa A, Nickel B, Daubenberger C.A, Guzman F, Pluschke G, Patarroyo M.E. Safety, tolerability and immunogenicity of new formulations of the Plasmodium falciparum malaria peptide SPf66 combined with the immunological adjuvant QS-21. Vaccine. 2002;20(17-18):2263-2277

Daubenberger C.A, Nickel B, Hübner B, Siegler U, Meini E, Pluschke G. Herpesvirus saimiri transformed T cells and peripheral blood mononuclear cells restimulate idential antigen-specific human T cell clones. J Immunol Methods. 2001;254(1-2):99-108

Nickel Beatrice. Human T cell responses to a semi-conserved sequence of the malaria vaccine candidate antigen MSP-1. Basel: Univ. Basel, 2001. Doctoral Thesis, University of Basel, Faculty of Science DOI: 10.5451/unibas-002406200

Kaminsky R, Nickel B, Holy A. Arrest of Trypanosoma brucei rhodesiense and T. brucei brucei in the S-phase of the cell cycle by (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine ((S)-HPMPA). Mol Biochem Parasitol. 1998;93(1):91-100