Eukaryotic translation elongation factor 1A (eEF1A) domain I from <em>S. cerevisiae</em> is required but not sufficient for inter-species... (Publications)
Ethanolamine phosphoglycerol (EPG) is a protein modification attached exclusively to eukaryotic elongation factor 1A (eEF1A). In mammals and plants, EPG is linked to conserved glutamate residues locat
Reduction in the proportion of fevers associated with <em>Plasmodium falciparum</em> parasitaemia in Africa: a systematic review (Publications)
BACKGROUND: Malaria is almost invariably ranked as the leading cause of morbidity and mortality in Africa. There is growing evidence of a decline in malaria transmission, morbidity and mortality over
The activities of current antimalarial drugs on the life cycle stages of <em>Plasmodium</em>: a comparative study with human and rodent parasites (Publications)
BACKGROUND: Malaria remains a disease of devastating global impact, killing more than 800,000 people every year-the vast majority being children under the age of 5. While effective therapies are avail
Modelling the cost-effectiveness of mass screening and treatment for reducing <em>Plasmodium falciparum</em> malaria burden (Publications)
BACKGROUND: Past experience and modelling suggest that, in most cases, mass treatment strategies are not likely to succeed in interrupting Plasmodium falciparum malaria transmission. However, this doe
A simulation model of African Anopheles ecology and population dynamics for the analysis of malaria transmission (Publications)
BACKGROUND: Malaria is one of the oldest and deadliest infectious diseases in humans. Many mathematical models of malaria have been developed during the past century, and applied to potential interven
Guidance for evidence-informed policies about health systems: rationale for and challenges of guidance development (Publications)
In the first paper in a three-part series on health systems guidance, Xavier Bosch-Capblanch and colleagues examine how guidance is currently formulated in low- and middle-income countries, and the ch