Paediatric referrals in rural Tanzania: the Kilombero District Study - a case series (Publications)
BACKGROUND: Referral is a critical part of appropriate primary care and of the Integrated Management of Childhood Illness (IMCI) strategy. We set out to study referrals from the aspect both of primary
Artesunate-mefloquine combination therapy in acute <em>Plasmodium falciparum</em> malaria in young children: a field study regarding neurological and... (Publications)
BACKGROUND: Mefloquine-artesunate combination therapy for uncomplicated falciparum malaria is one of the treatments used in African children. Data concerning neurological safety in adults and children
A tool box for operational mosquito larval control: preliminary results and early lessons from the Urban Malaria Control Programme in Dar es Salaam,... (Publications)
BACKGROUND: As the population of Africa rapidly urbanizes, large populations could be protected from malaria by controlling aquatic stages of mosquitoes if cost-effective and scalable implementation s
Global burden of human brucellosis: a systematic review of disease frequency (Publications)
BACKGROUND: This report presents a systematic review of scientific literature published between 1990-2010 relating to the frequency of human brucellosis, commissioned by WHO. The objectives were to id
"Pseudo-Beijing": evidence for convergent evolution in the direct repeat region of <em>Mycobacterium tuberculosis</em> (Publications)
BACKGROUND: Mycobacterium tuberculosis has a global population structure consisting of six main phylogenetic lineages associated with specific geographic regions and human populations. One particular
High prevalence of bovine tuberculosis in dairy cattle in central Ethiopia: implications for the dairy industry and public health (Publications)
BACKGROUND: Ethiopia has the largest cattle population in Africa. The vast majority of the national herd is of indigenous zebu cattle maintained in rural areas under extensive husbandry systems. Howev
<em>Plasmodium falciparum</em> heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors (Publications)
Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The malaria parasite Plasmodium falciparum employs antigenic variation of the major surface antigen PfEMP1, encoded
Virosome-formulated <em>Plasmodium falciparum</em> AMA-1 & CSP derived peptides as malaria vaccine: randomized phase 1b trial in semi-immune... (Publications)
BACKGROUND: This trial was conducted to evaluate the safety and immunogenicity of two virosome formulated malaria peptidomimetics derived from Plasmodium falciparum AMA-1 and CSP in malaria semi-immun