Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents (Publications)
A series of near-linear biphenyl benzimidazole diamidines 5a-h were synthesized from their respective diamidoximes (4a-h), through the bis-O-acetoxyamidoxime, followed by hydrogenation in glacial acet
Association of daily physical activity volume and intensity with COPD severity (Publications)
PURPOSE: The purpose of this study was to assess whether daily walking activity is indicative of disease severity in patients with COPD. METHODS: Daily activity was measured by accelerometry in 107 CO
Air pollution attributable postneonatal infant mortality in U.S. metropolitan areas: a risk assessment study (Publications)
BACKGROUND: The impact of outdoor air pollution on infant mortality has not been quantified. METHODS: Based on exposure-response functions from a U.S. cohort study, we assessed the attributable risk o
The first years of implementation of the Swiss National Environment and Health Action Plan (NEHAP): lessons for environmental health promotion (Publications)
The National Environment and Health Action Plans (NEHAPs) are a novel attempt to integrate environmental protection and health promotion in political programmes. Throughout Europe, about 40 NEHAPs hav
Environmental health indicators in policy evaluation (Publications)
In carrying out two projects involving environmental health indicators--a national environmental health programme evaluation and an international environmental health indicator system--in parallel, it
Analogues of thiolactomycin as potential anti-malarial and anti-trypanosomal agents (Publications)
A series of analogues of the naturally occurring antibiotic thiolactomycin (TLM) have been synthesised and evaluated for their ability to inhibit the growth of the malaria parasite, Plasmodium falcipa
Human infections with <em>Dicrocoelium dendriticum</em> in Kyrgyzstan: the tip of the iceberg? (Publications)
Abstract Dicrocoelium dendriticum is the causative agent of a rare food-borne zoonosis of the human biliary tract, dicrocoeliasis, for which few human prevalence data are available. Infection occurs t
The European Community Respiratory Health Survey: what are the main results so far? European Community Respiratory Health Survey II (Publications)
The European Community Respiratory Health Survey (ECRHS) was the first study to assess the geographical variation in asthma and allergy in adults using the same instruments and definitions. The databa
Dicationic phenyl-2,2'-bichalcophenes and analogues as antiprotozoal agents (Publications)
A series of phenyl-2,2'-bichalcophene diamidines 1a-h were synthesized from the corresponding dinitriles either via a direct reaction with LiN(TMS)(2), followed by deprotection with ethanolic HCl or t