Antiprotozoal activity of <em>Khaya anthotheca</em>, (Welv.) C.D.C. A plant used by chimpanzees for self medication (Publications)
ETHNOPHARMACOLOGICAL RELEVANCE: Khaya species, endemic to Africa and Madagascar, continues to be valuable in indigenous traditional medicine. Their bitter tasting barks are decocted to treat fevers, s
Effect of single-dose oral mefloquine on the morphology of adult <em>Schistosoma japonicum</em> in mice (Publications)
It has been recently documented that the antimalarial drug mefloquine shows in vivo activity against schistosomes. In the present study, we assessed the effect of mefloquine on the morphology of adult
Characterisation of a melamino nitroheterocycle as a potential lead for the treatment of human African trypanosomiasis (Publications)
This paper reports an evaluation of a melamine-nitroheterocycle, a potential lead for further development as an agent against human African trypanosomiasis (HAT). Studies on its efficacy, physicochemi
Pharmacokinetic comparison to determine the mechanisms underlying the differential efficacies of cationic diamidines against first- and second-stage... (Publications)
Human African trypanosomiasis (HAT), a neglected tropical disease, is fatal without treatment. Pentamidine, a cationic diamidine, has been used to treat first-stage (hemolymphatic) HAT since the 1940s
Using evidence to drive action: a "revolution in accountability" to implement quality care for better maternal and newborn health in Africa (Publications)
Introducing evidence-based accountability mechanisms at national and subnational levels into maternal newborn health programs can accelerate reductions in maternal and newborn mortality. Clearly packa