Clinical and epidemiologic phenotypes of childhood asthma (Publications)
Rationale: Clinical and epidemiologic approaches have identified two distinct sets of classifications for asthma and wheeze phenotypes. Objective: To compare epidemiologic phenotype definitions identi
Exposure to environmental microorganisms and childhood asthma (Publications)
BACKGROUND: Children who grow up in environments that afford them a wide range of microbial exposures, such as traditional farms, are protected from childhood asthma and atopy. In previous studies, ma
Asthma and obesity in children: current evidence and potential systems biology approaches (Publications)
Both obesity and asthma are highly prevalent, complex diseases modified by multiple factors. Genetic, developmental, lung mechanical, immunological and behavioural factors have all been suggested as p
Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood (Publications)
BACKGROUND: European cross-sectional studies have suggested that prenatal and postnatal farm exposure decreases the risk of allergic diseases in childhood. Underlying immunologic mechanisms are still
Progress in research, control and elimination of helminth infections in Asia (Publications)
Global health has substantially improved over the past 20 years. In low- and middle-income countries, in particular, great strives have been made in the control of communicable diseases, including hel
Multiparasitism and intensity of helminth infections in relation to symptoms and nutritional status among children: a cross-sectional study in... (Publications)
The occurrence and spatial distribution of intestinal helminth infection in children is fairly well understood. However, knowledge on how helminth infections govern intestinal morbidity is scarce. We
Isothermal microcalorimetry accurately detects bacteria, tumorous microtissues, and parasitic worms in a label-free well-plate assay (Publications)
Isothermal microcalorimetry is a label-free assay that allows monitoring of enzymatic and metabolic activities. The technique has strengths, but most instruments have a low throughput, which has limit
Evolutionary history and global spread of the <em>Mycobacterium tuberculosis</em> Beijing lineage (Publications)
Mycobacterium tuberculosis strains of the Beijing lineage are globally distributed and are associated with the massive spread of multidrug-resistant (MDR) tuberculosis in Eurasia. Here we reconstructe