How can Onchocerciasis elimination in Africa be accelerated? Modeling the impact of increased ivermectin treatment frequency and complementary vector... (Publications)
Background: Great strides have been made toward onchocerciasis elimination by mass drug administration (MDA) of ivermectin. Focusing on MDA-eligible areas, we investigated where the elimination goal c
Whole blood transcriptome changes following controlled human malaria infection in malaria pre-exposed volunteers correlate with parasite prepatent... (Publications)
Malaria continues to be one of mankind's most devastating diseases despite the many and varied efforts to combat it. Indispensable for malaria elimination and eventual eradication is the development o
Characterizing the biochemical response to <em>Schistosoma mansoni</em> infection and treatment with praziquantel in preschool and school aged... (Publications)
Schistosomiasis is a widespread chronic neglected tropical disease prevalent mostly in children in under-resourced rural areas. Its pathological effects have been clinically characterized, yet the mol
Metal hypersensitivity in patients with orthopaedic implant complications: a retrospective clinical study (Publications)
BACKGROUND: Hypersensitivity to metals as a cause of implant-related complications has been a subject of controversy. Projections indicate an increase in the frequency of joint replacements of between
The candidate blood-stage malaria vaccine P27A induces a robust humoral response in a fast track to the field phase I trial in exposed and non exposed... (Publications)
Background: P27A is an unstructured 104mer synthetic peptide from P. falciparum TEX1 blood-stage protein found to be the target of human antibodies inhibiting parasite growth. The present project aime
Safety, immunogenicity, and protective efficacy against controlled human malaria infection of<em> Plasmodium falciparum</em> sporozoites vaccine in... (Publications)
We are using controlled human malaria infection (CHMI) by direct venous inoculation (DVI) of cryopreserved, infectious Plasmodium falciparum (Pf) sporozoites (SPZ) (PfSPZ Challenge) to try to reduce t
Measuring early childhood development at a global scale: evidence from the caregiver-reported early development instruments (Publications)
Despite global interest in supporting and monitoring early childhood development (ECD), few valid and reliable tools exist for capturing ECD at scale across cultural contexts. This study describes the
Measuring subjective flood resilience in suburban Dakar: a before–after evaluation of the “Live with water” project (Publications)
In the last decade, sub-Saharan African countries have taken various measures to plan for and adapt to floods in order to reduce exposure and its impacts on human health, livelihoods, and infrastructu