Atherogenesis in youth - early consequence of adolescent smoking (Publications)
BACKGROUND: Cigarette smoking is a prevalent risk behavior among adolescents and tracks into adulthood. Little is known on the early impact of smoking on the vasculature in adolescence, although smoki
Long-term effects of elemental composition of particulate matter on inflammatory blood markers in European cohorts (Publications)
BACKGROUND: Epidemiological studies have associated long-term exposure to ambient particulate matter with increased mortality from cardiovascular and respiratory disorders. Systemic inflammation is a
The locus <em>C11orf30</em> increases susceptibility to poly-sensitization (Publications)
A number of genetic variants have been associated with allergic sensitization, but whether these are allergen specific or increase susceptibility to poly-sensitization is unknown. Using data from the
Changes in IgE sensitization and total IgE levels over 20 years of follow-up (Publications)
BACKGROUND: Cross-sectional studies have reported a lower prevalence of sensitization in older adults, but few longitudinal studies have examined whether this is an aging or a year-of-birth cohort eff
Spirometer replacement and serial lung function measurements in population studies: results from the SAPALDIA study (Publications)
The Swiss Cohort Study on Air Pollution and Lung and Heart Disease in Adults (SAPALDIA), a population cohort study, used heated-wire spirometers in 1991 and 2002 and then ultrasonic spirometers in 201
Follow-up on genome-wide main effects: do polymorphisms modify the air pollution effect on lung function decline in adults? (Publications)
Improved air quality has been found associated with attenuated age-related decline in lung function. But whether genetic polymorphisms strongly associated with lung function play a modifying role in t
Forschung für Generationen (Publications)
Die ehemalige "Luft- und Lungen-Studie" SAPALDIA ist 20 Jahre alt geworden. Forscherinnen und Forscher aus verschiedensten Disziplinen untersuchen seit Jahren das Zusammenspiel von Umwelt und Gesundhe
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets (Publications)
Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function and is the third leading cause of death globally. Through genome-wide association discovery in 48,943 individuals