Using lung cancer mortality to indirectly approximate smoking patterns in space (Publications)
Smoking is the leading cause of lung cancer. Non-smoking factors have been associated with the disease. Existing Swiss survey data only capture the country partially and temporal coverage does not all
Antiviral innate immune activation in HIV infected adults negatively affects H1/IC31(R) induced vaccine-specific memory CD4+ T cells (Publications)
Tuberculosis (TB) remains a global health problem, with vaccination being a necessary strategy for disease containment and elimination. A TB vaccine should be safe and immunogenic as well as efficacio
Human African trypanosomiasis prevention, treatment and control costs: a systematic review (Publications)
The control and eventual elimination of human African trypanosomiasis (HAT) requires the expansion of current control and surveillance activities. A systematic review of the published literature on th
Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3,... (Publications)
BACKGROUND: The efficacy and safety of the RTS,S/AS01 candidate malaria vaccine during 18 months of follow-up have been published previously. Herein, we report the final results from the same trial, i
A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria (Publications)
Malaria is one of the most significant causes of childhood mortality, but disease control efforts are threatened by resistance of the Plasmodium parasite to current therapies. Continued progress in co
Are well functioning civil registration and vital statistics systems associated with better health outcomes? (Publications)
In this Series paper, we examine whether well functioning civil registration and vital statistics (CRVS) systems are associated with improved population health outcomes. We present a conceptual model
Microbial and chemical contamination of water, sediment and soil in the Nakivubo wetland area in Kampala, Uganda (Publications)
The reuse of domestic and industrial wastewater in urban settings of the developing world may harm the health of people through direct contact or via contaminated urban agricultural products and drink
Prodrugs of reverse fosmidomycin analogues (Publications)
Fosmidomycin inhibits IspC (Dxr, 1-deoxy-d-xylulose 5-phosphate reductoisomerase), a key enzyme in nonmevalonate isoprenoid biosynthesis that is essential in Plasmodium falciparum. The drug has been u
Using health and demographic surveillance system (HDSS) data to analyse geographical distribution of socio-economic status: an experience from... (Publications)
Continuous monitoring in health and demographic surveillance sites (HDSS) allows for collection of longitudinal demographic data, health related, and socio-economic indicators of the site population.
Southern East Asian origin and coexpansion of <em>Mycobacterium tuberculosis</em> Beijing family with Han Chinese (Publications)
The Beijing family is the most successful genotype of Mycobacterium tuberculosis and responsible for more than a quarter of the global tuberculosis epidemic. As the predominant genotype in East Asia,