HIV co-infection is associated with reduced <em>Mycobacterium tuberculosis</em> transmissibility in sub-Saharan Africa (Publications)
Persons living with HIV are known to be at increased risk of developing tuberculosis (TB) disease upon infection with Mycobacterium tuberculosis (Mtb). However, it has remained unclear how HIV co-infe
On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity (Publications)
To combat the global burden of malaria, development of new drugs to replace or complement current therapies is urgently required. Here, we show that the compound MMV1557817 is a selective, nanomolar i
Availability of published evidence on coverage, cost components, and funding support for digitalisation of infectious disease surveillance in Africa,... (Publications)
BACKGROUND: The implementation of digital disease surveillance systems at national levels in Africa have been challenged by many factors. These include user applicability, utility of IT features but a
Population assessment of health system performance in 16 countries (Publications)
OBJECTIVE: To demonstrate how the new internationally comparable instrument, the People's Voice Survey, can be used to contribute the perspective of the population in assessing health system performan
Antibiotic point prevalence survey and antimicrobial resistance in hospitalized patients across Peruvian reference hospitals (Publications)
BACKGROUND: Peru reports higher levels than other countries in Latin America of resistance to antimicrobials among Gram-positive and Gram-negative bacteria, however data on antibiotic use in Peru are
Bedaquiline resistance in patients with drug-resistant tuberculosis in Cape Town, South Africa: a retrospective longitudinal cohort study (Publications)
BACKGROUND: Bedaquiline is a life-saving tuberculosis drug undergoing global scale-up. People at risk of weak tuberculosis drug regimens are a priority for novel drug access despite the potential sour