Incidence of asthma and net change in symptoms in relation to changes in obesity (Publications)
The incidence of asthma has been reported to be associated with obesity. An alternative analysis, of net change in prevalence, does not require exclusion of those with asthma at baseline.Follow-up dat
Oral treatment for <em>Mycobacterium ulcerans</em> infection: results from a pilot study in Benin (Publications)
Mycobacterium ulcerans infection is responsible for severe skin lesions in sub-Saharan Africa. We enrolled 30 Beninese patients with Buruli ulcers in a pilot study to evaluate efficacy of an oral chem
Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase (Publications)
Novel quinazoline-type compounds were designed as inhibitors of the parasite specific enzyme trypanothione reductase (TR), and their biological activities were evaluated. Some of our compounds inhibit
Cost-effectiveness of invasive versus medical management of elderly patients with chronic symptomatic coronary artery disease. Findings of the... (Publications)
AIM: To compare benefits and costs of invasive versus medical management in elderly patients with chronic angina. METHODS AND RESULTS: In a predefined subgroup of 188 patients of the Trial of Invasive
Modelling vertical transmission in vector-borne diseases with applications to Rift Valley fever (Publications)
We present two ordinary differential equation models for Rift Valley fever (RVF) transmission in cattle and mosquitoes. We extend existing models for vector-borne diseases to include an asymptomatic h