IS6<em>110</em>-based global phylogeny of <em>Mycobacterium tuberculosis</em> (Publications)
IS6110, a Mycobacterium tuberculosis complex species-specific insertion element, is targeted primarily for DNA fingerprinting of M. tuberculosis strains. The number and chromosomal positions of copies
Interaction of monobenzamidine-linked trypanocides with the <em>Trypanosoma brucei</em> P2 aminopurine transporter (Publications)
Single benzamidine group-carrying compounds were shown to interact with the Trypanosoma brucei P2 aminopurine transporter. Replacement of the amidine with a guanidine group decreased affinity. Trypano
Spatial analysis of malaria transmission parameters in the rice cultivation area of office du Niger, Mali (Publications)
The effects of rice growth environment on malaria transmission, taking into account spatial correlation, were assessed in the Office du Niger, Mali. Between April 1999 to January 2001, 8 quarterly ent
Association between short term exposure to fine particulate matter and heart rate variability in older subjects with and without heart disease (Publications)
BACKGROUND: Short term increases in exposure to particulate matter (PM) air pollution are associated with increased cardiovascular morbidity and mortality. The mechanism behind this effect is unclear,
Associations between infections and clinical outcome parameters in status epilepticus: a retrospective 5-year cohort study (Publications)
Purpose: Status epilepticus (SE) represents a life-threatening condition, requiring pharmacologic therapy and neurointensive care. Infectious complications in SE are suspected to be frequent and worse
Antimycobacterial, antiprotozoal and cytotoxic potential of twenty-one brown algae (Phaeophyceae) from British and Irish waters (Publications)
In the continuation of our research on seaweeds, crude extracts of 21 brown algae collected from the south coast of England and the west coast of Ireland were screened for in vitro trypanocidal, leish
2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage <em>Plasmodium</em> infections (Publications)
Acetylenic fatty acids are known to display several biological activities, but their antimalarial activity has remained unexplored. In this study, we synthesized the 2-, 5-, 6-, and 9-hexadecynoic aci