Efficacy study of novel diamidine compounds in a <em>Trypanosoma evansi</em> goat model (Publications)
Three diamidines (DB 75, DB 867 and DB 1192) were selected and their ability to cure T. evansi experimentally infected goats was investigated. A toxicity assessment and pharmacokinetic analysis of the
A randomized placebo-controlled phase a malaria vaccine trial of two virosome-formulated synthetic peptides in healthy adult volunteers (Publications)
BACKGROUND AND OBJECTIVES: Influenza virosomes represent an innovative human-compatible antigen delivery system that has already proven its suitability for subunit vaccine design. The aim of the study
Genetic reconstruction of protozoan rRNA decoding sites provides a rationale for paromomycin activity against <em>Leishmania</em> and... (Publications)
Aminoglycoside antibiotics target the ribosomal decoding A-site and are active against a broad spectrum of bacteria. These compounds bind to a highly conserved stem-loop-stem structure in helix 44 of
Tick-borne diseases in Switzerland and climate change (Publications)
Tick-borne diseases are the most common vector-borne diseases in Europe. In Central Europe, the tick Ixodes ricinus is responsible for most tick bites. Next to tick borne encephalitis (TBE or in Germa