<em>Trypanosoma brucei brucei</em>: a model for cerebral trypanosomiasis in mice--an immunological, histological and electronmicroscopic study (Publications)
The successful induction of cerebral trypanosomiasis in ordinary laboratory mice using Trypanosoma brucei brucei is reported. Sequential studies demonstrated the presence of trypanosomes in the inters
Novel nitro(triazole/imidazole)-based heteroarylamides/ sulfonamides as potential antitrypanosomal agents (Publications)
We have previously shown that 3-nitro-1H-1,2,4-triazole-based arylamides and arylsulfonamides demonstrate significant activity in vitro against Trypanosoma cruzi, the causative parasite of Chagas dise
Cost of near-roadway and regional air pollution-attributable childhood asthma in Los Angeles county (Publications)
BACKGROUND: Emerging evidence suggests that near-roadway air pollution (NRP) exposure causes childhood asthma. The associated costs are not well documented. OBJECTIVE: We estimated the cost of childho
<em>In vitro</em> antiplasmodial screening of ethnopharmacologically selected South African plant species used for the treatment of malaria (Publications)
ETHNOPHARMACOLOGICAL RELEVANCE: The investigated plant species are traditionally used by Venda people of South Africa in the treatment of malaria and associated symptoms. To evaluate the in vitro anti
<em>Trypanosoma brucei</em> eflornithine transporter AAT6 is a low-affinity low-selective transporter for neutral amino acids (Publications)
Amino acid transporters are crucial for parasite survival since the cellular metabolism of parasitic protozoa depends on the up-take of exogenous amino acids. Amino acid transporters are also of high
Stimulation of hamster and human lymphocyte cultures by soluble egg antigens (SEA) of <em>Schistosoma haematobium </em>and <em>S. mansoni</em> (Publications)
Soluble egg and adult worm antigen preparations of Schistosoma haematobium and S. mansoni were tested in hamster and human lymphocyte cultures. Primed lymphocytes from infected donors showed a marked