Associations of inter- and intraday temperature change with mortality (Publications)
In this study we evaluated the association between temperature variation and mortality and compared it with the contribution due to mean daily temperature in 6 cities with different climates. Quasi-Po
Sociocultural determinants of anticipated oral cholera vaccine acceptance in three African settings: a meta-analytic approach (Publications)
BACKGROUND: Controlling cholera remains a significant challenge in Sub-Saharan Africa. In areas where access to safe water and sanitation are limited, oral cholera vaccine (OCV) can save lives. Establ
Managing research and surveillance projects in real-time with a novel open-source eManagement tool designed for under-resourced countries (Publications)
OBJECTIVE: A software tool is developed to facilitate data entry and to monitor research projects in under-resourced countries in real-time. METHODS: The eManagement tool "odk_planner" is written in t
Stakeholders' opinions and questions regarding the anticipated malaria vaccine in Tanzania (Publications)
BACKGROUND: Within the context of combined interventions, malaria vaccine may provide additional value in malaria prevention. Stakeholders' perspectives are thus critical for informed recommendation o
Development and validation of an enantioselective LM-MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in... (Publications)
Praziquantel (PZQ) is the treatment of choice against various trematode and cestode infections. To study the pharmacokinetics of PZQ in patients infected with the liver fluke Opisthorchis viverrini, w
Efficacy and safety of oxantel pamoate in school-aged children infected with <em>Trichuris trichiura</em> on Pemba island, Tanzania: a parallel,... (Publications)
BACKGROUND: Commonly used drugs for preventive chemotherapy against soil-transmitted helminths (ie, albendazole and mebendazole) show low efficacy against Trichuris trichiura. Recent studies with oxan
Cross-reactivity pattern of Asian and American human gnathostomiasis in western blot assays using crude antigens prepared from <em>Gnathostoma... (Publications)
Gnathostomiasis is a zoonotic parasitosis endemic in many Asian and some Latin American countries. Most human infections are caused by Gnathostoma spinigerum in Asia and Gnathostoma binucleatum in the
Miltefosine for mucosal and complicated cutaneous old world leishmaniasis: a case series and review of the literature (Publications)
Complicated Old World cutaneous leishmaniasis (OWCL) and Old World mucosal leishmaniasis (OWML) constitute an indication for systemic treatment. To date, there no controlled clinical studies that comp
Pharmacokinetic study of praziquantel enantiomers and its main metabolite R-trans-4-OH-PZQ in plasma, blood and dried blood spots in <em>Opisthorchis... (Publications)
BACKGROUND: Praziquantel (PZQ) is the treatment of choice for infections with the liver fluke Opisthorchis viverrini, a major health problem in Southeast Asia. However, pharmacokinetic (PK) studies in
Validation of a point-of-care circulating cathodic antigen urine cassette test for <em>Schistosoma mansoni</em> diagnosis in the Sahel, and potential... (Publications)
On the shores of Lake Chad, schistosomiasis among mobile pastoralists was investigated in a field laboratory. Point-of-care circulating cathodic antigen (POC-CCA) cassette test, reagent strips, and fi