Approved oncology drugs lack <em>in vivo</em> activity against <em>Trichuris muris</em> despite <em>in vitro</em> activity (Publications)
Infections with soil-transmitted helminths (STHs) are considered among the most persistent global health problems. The few available drugs have limitations including low efficacy against Trichuris tri
Road traffic noise, blood pressure and heart rate: pooled analyses of harmonized data from 88,336 participants (Publications)
INTRODUCTION: Exposure to road traffic noise may increase blood pressure and heart rate. It is unclear to what extent exposure to air pollution may influence this relationship. We investigated associa
Parental attitudes towards measles vaccination in the canton of Aargau, Switzerland: a latent class analysis (Publications)
BACKGROUND: Despite the successes of routine national childhood vaccination programmes, measles remains a public health concern. The purpose of this paper is to investigate how patterns of parental at
Mass mosquito trapping for malaria control in western Kenya: study protocol for a stepped wedge cluster-randomised trial (Publications)
BACKGROUND: Increasing levels of insecticide resistance as well as outdoor, residual transmission of malaria threaten the efficacy of existing vector control tools used against malaria mosquitoes. The
The effect of mass mosquito trapping on malaria transmission and disease burden (SolarMal): a stepped-wedge cluster-randomised trial (Publications)
Odour baits can attract host-seeking Anopheles mosquitoes indoors and outdoors. We assessed the effects of mass deployment of odour-baited traps on malaria transmission and disease burden. We installe
Successive introduction of four new vaccines in Rwanda: high coverage and rapid scale up of Rwanda's expanded immunization program from 2009 to... (Publications)
As the pace of vaccine uptake accelerates globally, there is a need to document low-income country experiences with vaccine introductions. Over the course of five years, the government of Rwanda rolle
A crossover study to evaluate the diversion of malaria vectors in a community with incomplete coverage of spatial repellents in the Kilombero Valley,... (Publications)
BACKGROUND: Malaria elimination is unlikely to occur if vector control efforts focus entirely on transmission occurring indoors without addressing vectors that bite outdoors and outside sleeping hours
Evaluation of giant African pouched rats for detection of pulmonary tuberculosis in patients from a high-endemic setting (Publications)
BACKGROUND: This study established evidence about the diagnostic performance of trained giant African pouched rats for detecting Mycobacterium tuberculosis in sputum of well-characterised patients wit
Cure frailty models for survival data: application to recurrences for breast cancer and to hospital readmissions for colorectal cancer (Publications)
Owing to the natural evolution of a disease, several events often arise after a first treatment for the same subject. For example, patients with a primary invasive breast cancer and treated with breas
cART prescription trends in a prospective HIV cohort in rural Tanzania from 2007 to 2011 (Publications)
Comprehensive information on combined antiretroviral therapy (cART) regimens in rural Sub-Saharan Africa over time is scarce, particularly on the use of stavudine (d4T) and second-line regimens. Since