A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample (Publications)
RATIONALE: Lung function measures are heritable traits that predict population morbidity and mortality and are essential for the diagnosis of chronic obstructive pulmonary disease (COPD). Variations i
Is diabetes a risk factor for a severe clinical presentation of dengue? Review and meta-analysis (Publications)
BACKGROUND: The mean age of acute dengue has undergone a shift towards older ages. This fact points towards the relevance of assessing the influence of age-related comorbidities, such as diabetes, on
The relevance of commuter and work/school exposure in an epidemiological study on traffic-related air pollution (Publications)
Exposure during transport and at non-residential locations is ignored in most epidemiological studies of traffic-related air pollution. We investigated the impact of separately estimating NO2 long-ter
Predictive value of clinical and laboratory features for the main febrile diseases in children living in Tanzania: a prospective observational study (Publications)
BACKGROUND: To construct evidence-based guidelines for management of febrile illness, it is essential to identify clinical predictors for the main causes of fever, either to diagnose the disease when
Single-dose hepatitis A immunization: 7.5-year observational pilot study in Nicaraguan children to assess protective effectiveness and humoral immune... (Publications)
BACKGROUND: Universal 2-dose hepatitis A virus (HAV) vaccination of toddlers effectively controls hepatitis A. High vaccine costs, however, impede implementation in endemic countries. To test single-d
The influence of HIV on the evolution of <em>Mycobacterium tuberculosis</em> (Publications)
HIV significantly affects the immunological environment during tuberculosis co-infection, and therefore may influence the selective landscape upon which M. tuberculosis evolves. To test this hypothesi