Novel high-throughput screening method using quantitative PCR to determine the antimicrobial susceptibility of <em>Orientia tsutsugamushi... (Publications)
Objectives: To develop a method to enable the large-scale antimicrobial susceptibility screening of Orientia tsutsugamushi clinical isolates, using one timepoint and one concentration of antibiotics t
Case report: concurrent sympatric scrub typhus and Japanese spotted fever in Japan (Publications)
Scrub typhus and Japanese spotted fever-both rickettsial diseases-are endemic and notifiable in Japan and may cause a fatal outcome without prompt treatment. Here we present the first case of a concur
Identifying risk of viral failure in treated HIV-infected patients using different measures of adherence: the Antiretroviral Therapy Cohort... (Publications)
Adherence to antiretroviral therapy (ART) is critical for successful treatment of Human Immunodeficiency Virus (HIV), but comparisons across settings are difficult because adherence is measured in dif
Methionine-containing rhabdopeptide/xenortide-like peptides from heterologous expression of the biosynthetic gene cluster <em>kj12ABC</em> in... (Publications)
Seven new methionine-containing rhabdopeptide/xenortide-like peptides (1-7) were identified from Escherichia coli expressing the rhabdopeptide/xenortide-like peptide biosynthetic gene cluster kj12ABC
Baseline exposure, antibody subclass, and hepatitis B response differentially affect malaria protective immunity following RTS,S/AS01E vaccination in... (Publications)
BACKGROUND: The RTS,S/AS01E vaccine provides partial protection against malaria in African children, but immune responses have only been partially characterized and do not reliably predict protective
Environmental and health data needed to develop national surveillance systems in industrially contaminated sites (Publications)
BACKGROUND: this paper is based upon work from COST Action ICSHNet. Public health surveillance (PHS) of industrially contaminated sites (ICSs) is likely to play a role in supporting the monitoring of
Integrating standardized whole genome sequence analysis with a global <em>Mycobacterium tuberculosis</em> antibiotic resistance knowledgebase (Publications)
Drug-resistant tuberculosis poses a persistent public health threat. The ReSeqTB platform is a collaborative, curated knowledgebase, designed to standardize and aggregate global Mycobacterium tubercul
<em>In vitro</em> and<em> in vivo</em> drug-drug interaction study of the effects of ivermectin and oxantel pamoate on tribendimidine (Publications)
Soil-transmitted helminth (STH) infections still remain a major health problem in poor rural settings. The lack of efficacious drugs against all STH species raises the interest in drug combinations. D
A review of exposure assessment methods for epidemiological studies of health effects related to industrially contaminated sites (Publications)
BACKGROUND: this paper is based upon work from COST Action ICSHNet. Health risks related to living close to industrially contaminated sites (ICSs) are a public concern. Toxicology-based risk assessmen
Challenges and lessons from conducting a paediatric clinical trial in sub-Saharan Africa: the case of the praziquantel oral dispersible tablets phase... (Publications)
The importance of implementing paediatric clinical trials for neglected tropical diseases (NTDs) in compliance with the Good Clinical Practices of the International Conference of Harmonisation (ICH-GC