Immunologic-based diagnosis of latent tuberculosis among children less than 5 years of age exposed and unexposed to tuberculosis in Tanzania:... (Publications)
BACKGROUND: Childhood tuberculosis (TB) is acquired following exposure to an infectious TB case, often within the household. We prospectively screened children 6-59 months of age, exposed and unexpose
Adverse impact of nocturnal transportation noise on glucose regulation in healthy young adults: effect of different noise scenarios (Publications)
BACKGROUND: Epidemiological evidence indicates an association between transportation noise exposure and a higher risk of developing type 2 diabetes. Sleep disturbances are thought to be one of the mec
Population pharmacokinetics of the antimalarial amodiaquine: a pooled analysis to optimize dosing (Publications)
Amodiaquine plus artesunate is the recommended antimalarial treatment in many malaria-endemic countries. However, pediatric doses are largely based on a linear extrapolation from adult doses. We poole
Using dried blood spots to facilitate therapeutic drug monitoring of antiretroviral drugs in resource-poor regions (Publications)
Objectives: We evaluated whether dried blood spots (DBS) are suitable to monitor combined ART when samples are collected in rural Tanzania and transported over a long distance to a specialized bioanal
Comparative genomics of <em>Mycobacterium africanum</em> lineage 5 and lineage 6 from Ghana suggests distinct ecological niches (Publications)
Mycobacterium africanum (Maf) causes a substantial proportion of human tuberculosis in some countries of West Africa, but little is known on this pathogen. We compared the genomes of 253 Maf clinical