Home-based and facility-based directly observed therapy of tuberculosis treatment under programmatic conditions in urban Tanzania (Publications)
INTRODUCTION: Decentralization of Directly Observed Treatment (DOT) for tuberculosis (TB) to the community (home-based DOT) has improved the coverage of TB treatment and reduced the burden to the heal
Spatiotemporal co-existence of two <em>Mycobacterium ulcerans</em> clonal complexes in the Offin River valley of Ghana (Publications)
In recent years, comparative genome sequence analysis of African Mycobacterium ulcerans strains isolated from Buruli ulcer (BU) lesion specimen has revealed a very limited genetic diversity of closely
Malaria intervention scale-up in Africa: effectiveness predictions for health programme planning tools, based on dynamic transmission modelling (Publications)
BACKGROUND: Scale-up of malaria prevention and treatment needs to continue to further important gains made in the past decade, but national strategies and budget allocations are not always evidence-ba
Gaining and sustaining schistosomiasis control: study protocol and baseline data prior to different treatment strategies in five African countries (Publications)
BACKGROUND: The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) was established in 2008 to answer strategic questions about schistosomiasis control. For programme managers,
A systematic review of supportive supervision as a strategy to improve primary healthcare services in sub-Saharan Africa (Publications)
BACKGROUND: It may be assumed that supportive supervision effectively builds capacity, improves the quality of care provided by frontline health workers, and positively impacts clinical outcomes. Evid
Applied statistical training to strengthen analysis and health research capacity in Rwanda (Publications)
BACKGROUND: To guide efficient investment of limited health resources in sub-Saharan Africa, local researchers need to be involved in, and guide, health system and policy research. While extensive sur
Asthma and the menopause: a systematic review and meta-analysis (Publications)
OBJECTIVE: To review the available literature to determine whether the menopausal transition is associated with asthma incidence.METHODS: We performed a systematic review and meta-analysis of cohort a
Comparing a disease-specific and a generic health-related quality of life instrument in subjects with asthma from the general population (Publications)
ABSTRACT: BACKGROUND: Few epidemiologic studies have assessed health-related quality of life (HRQL) of asthma patients from a general population and it is unclear which instrument is best suitable for
Joint effect of obesity and TNFA variability on asthma: two international cohort studies (Publications)
Obesity is a risk factor for asthma. Adipose tissue expresses pro-inflammatory molecules including tumour necrosis factor (TNF), and levels of TNF are also related to polymorphisms in the TNF-alpha (T