A new double-antibody sandwich ELISA targeting <em>Plasmodium falciparum</em> aldolase to evaluate anti-malarial drug sensitivity (Publications)
BACKGROUND: The standard in vitro test to assess anti-malarial activity of chemical compounds is the [3H]hypoxanthine incorporation assay. It is a radioactivity-based method to measure DNA replication
A research agenda for malaria eradication: vector control (Publications)
Different challenges are presented by the variety of malaria transmission environments present in the world today. In each setting, improved control for reduction of morbidity is a necessary first ste
Activity of oxantel pamoate monotherapy and combination chemotherapy against <em>Trichuris muris</em> and hookworms: revival of an old drug (Publications)
BACKGROUND: It is widely recognized that only a handful of drugs are available against soil-transmitted helminthiasis, all of which are characterized by a low efficacy against Trichuris trichiura, whe
Access to artemisinin-based anti-malarial treatment and its related factors in rural Tanzania (Publications)
BACKGROUND: Artemisinin-based combination treatment (ACT) has been widely adopted as one of the main malaria control strategies. However, its promise to save thousands of lives in sub-Saharan Africa d
Air pollution and atherosclerosis: new evidence to support air quality policies (Publications)
Nino Künzli discusses a large new cohort study that provides some of the first human evidence for the impact of air pollution on the development of atherosclerosis.
Genetic characterization of<em> Legionella pneumophila</em> isolated from a common watershed in Comunidad Valenciana, Spain (Publications)
Legionella pneumophila infects humans to produce legionellosis and Pontiac fever only from environmental sources. In order to establish control measures and study the sources of outbreaks it is essent
<em>In vitro</em> and <em>in vivo</em> efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections (Publications)
BACKGROUND: Few effective drugs are available for soil-transmitted helminthiases and drug resistance is of concern. In the present work, we tested the efficacy of the veterinary drug monepantel, a pot