Cost effectiveness of seasonal intermittent preventive treatment using amodiaquine & artesunate or sulphadoxine-pyrimethamine in Ghanaian children (Publications)
BACKGROUND: Intermittent preventive treatment for malaria in children (IPTc) involves the administration of a full course of an anti-malarial treatment to children under 5 years old at specified time
Carotid intima-media thickness as a biomarker of subclinical atherosclerosis (Publications)
Intima-media thickness of the carotid artery (CIMT) and its increase is associated with several cardiovascular risk factors and manifest cardiovascular diseases. CIMT is suggested to be an important b
Socially-marketed rapid diagnostic tests and ACT in the private sector: ten years of experience in Cambodia (Publications)
Whilst some populations have recently experienced dramatic declines in malaria, the majority of those most at risk of Plasmodium falciparum malaria still lack access to effective treatment with artemi
Incidence and predictors of immune reconstitution inflammatory syndrome in a rural area of Mozambique (Publications)
BACKGROUND: There is limited data on the epidemiology of Immune Reconstitution Inflammatory Syndrome (IRIS) in rural sub-Saharan Africa. A prospective observational cohort study was conducted to asses
Adherence to prescribed artemisinin-based combination therapy in Garissa and Bunyala districts, Kenya (Publications)
BACKGROUND: Following the development of resistance to anti-malarial mono-therapies, malaria endemic countries in Africa now use artemisinin-based combination therapy (ACT) as recommended first-line t
Estimating population access to insecticide-treated nets from administrative data: correction factor is needed (Publications)
BACKGROUND: Population access to insecticide-treated nets (ITN) is usually determined from survey data. However, for planning purposes it is necessary to estimate this indicator between surveys. Two d
Perceptions of, attitudes towards and barriers to male involvement in newborn care in rural Ghana, West Africa: a qualitative analysis (Publications)
BACKGROUND: Male involvement in various health practices is recognized as an important factor in improving maternal and child health outcomes. Male involvement interventions involve men in a variety o
The epidemiology of HIV and HSV-2 infections among women participating in microbicide and vaccine feasibility studies in Northern Tanzania (Publications)
OBJECTIVES: To prepare for future HIV prevention trials, we conducted prospective cohort studies among women working in food and recreational facilities in northern Tanzania. We examined the prevalenc
Genomic diversity among drug sensitive and multidrug resistant isolates of <em>Mycobacterium tuberculosis</em> with identical DNA fingerprints (Publications)
BACKGROUND: Mycobacterium tuberculosis complex (MTBC), the causative agent of tuberculosis (TB), is characterized by low sequence diversity making this bacterium one of the classical examples of a gen
A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion (Publications)
LJ001 is a lipophilic thiazolidine derivative that inhibits the entry of numerous enveloped viruses at non-cytotoxic concentrations (IC50?0.5 µM), and was posited to exploit the physiological differen