Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents (Publications)
We report herein the synthesis and trypanocidal profile of new (E)-cinnamic N-acylhydrazones (NAHs) designed by exploiting molecular hybridization between the potent cruzain inhibitors (E)-1-(benzo[d]
Perception of traffic noise emission in Basel City canton in comparison to actually measured noise levels (Publications)
The objective of this study was to assess to what extent the subjective annoyance is influenced by the actually measured or calculated street traffic noise and by sociodemographic factors. In the stud
Pharmacotherapy, vaccines and malaria advice for HIV-infected travellers (Publications)
Since the introduction of effective antiretroviral therapy (ART), HIV-infected individuals are travelling more frequently and international travel has become much safer. Specific concerns include the
Risk factors for chronic obstructive pulmonary disease in a European cohort of young adults (Publications)
RATIONALE: Few studies have investigated the factors associated with the early inception of chronic obstructive pulmonary disease (COPD). OBJECTIVE: We investigated COPD risk factors in an internation
Immunoglobulin kappa light-chain V, J, and C gene sequences of the owl monkey <em>Aotus nancymaae</em> (Publications)
Sequences of Aotus nancymaae immunoglobulin kappa light-chain rearrangements were analyzed after reverse transcription polymerase chain reaction. Among 22 in-frame rearrangements analyzed, 12 IGKV gen
DNA binding affinity of bisguanidine and bis (2-aminoimidazoline) derivatives with in vivo antitrypanosomal activity (Publications)
A new antitrypanosomal hit compound that cures an acute (STIB 900) mouse model of Trypanosoma brucei rhodesiense trypanosomiasis is described. This bis(2-aminoimidazolinium) dicationic compound proved
Disesquiterpene and sesquiterpene coumarins from <em>Ferula pseudalliacea</em>, and determination of their absolute configurations (Publications)
The first disesquiterpene coumarin, sanandajin, five sesquiterpene coumarins, kamolonol acetate, fekrynol acetate, ethyl galbanate, methyl galbanate, farnesiferol B, and a sesquiterpene, aristolone, w
Sexual compatibility among <em>Trypanosoma brucei</em> isolates from an epidemic area in southeastern Uganda (Publications)
For the first time, two clones of Trypanosoma brucei from the same epidemic area in southeastern Uganda were successfully crossed. The cotransmission experiments were as close to natural conditions as