Hemolysis after oral artemisinin combination therapy for uncomplicated <em>Plasmodium falciparum</em> malaria (Publications)
Episodes of delayed hemolysis 2-6 weeks after treatment of severe malaria with intravenous artesunate have been described. We performed a prospective observational study of patients with uncomplicated
<em>In vitro </em>and <em>in vivo</em> drug interaction study of two lead combinations, oxantel pamoate plus albendazole and albendazole plus... (Publications)
The current treatments against Trichuris trichiura, albendazole and mebendazole, are only poorly efficacious. Therefore, combination chemotherapy was recommended for treating soil-transmitted helminth
Mapping of research on maternal health interventions in low- and middle-income countries: a review of 2292 publications between 2000 and 2012 (Publications)
BACKGROUND: Progress in achieving maternal health goals and the rates of reductions in deaths from individual conditions have varied over time and across countries. Assessing whether research prioriti
Travel medicine and mHealth technology: a study using smartphones to collect health data during travel (Publications)
BACKGROUND: mHealth methodology such as smartphone applications offers new opportunities to capture the full range of health risks during travel in real time. Our study aims to widen the scope of trav
Correcting India's chronic shortage of drug inspectors to ensure the production and distribution of safe, high-quality medicines (Publications)
BACKGROUND: Good drug regulation requires an effective system for monitoring and inspection of manufacturing and sales units. In India, despite widespread agreement on this principle, ongoing shortage
Discovery and characterization of ACT-451840: an antimalarial drug with a novel mechanism of action (Publications)
More than 40 % of the world's population is at risk of being infected with malaria. Most malaria cases occur in the countries of sub-Saharan Africa, Central and South America, and Asia. Resistance to
Regular family breakfast was associated with children's overweight and parental education: results from the ENERGY cross-sectional study (Publications)
INTRODUCTION: This study aims to assess (i) the prevalence of having regular family breakfast, lunch, dinner (i.e. 5-7days/week together with their family) among 10-12year olds in Europe, (ii) the ass
Characterization of novel antimalarial compound ACT-451840: preclinical assessment of activity and dose-efficacy modeling (Publications)
BACKGROUND: Artemisinin resistance observed in Southeast Asia threatens the continued use of artemisinin-based combination therapy in endemic countries. Additionally, the diversity of chemical mode of
Ivermectin treatment and sanitation effectively reduce <em>Strongyloides stercoralis</em> infection risk in rural communities in Cambodia (Publications)
BACKGROUND: Strongyloides stercoralis is the only soil-transmitted helminth with the ability to replicate within its host, leading to long-lasting and potentially fatal infections. It is ubiquitous an