Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications (Publications)
BACKGROUND: Intermittent preventive treatment (IPTi) with sulphadoxine-pyrimethamine (SP) in infants resulted in different estimates of clinical malaria protection in two trials that used the same pro
Exposure to moderate air pollution during late pregnancy and cord blood cytokine secretion in healthy neonates (Publications)
BACKGROUND/OBJECTIVES: Ambient air pollution can alter cytokine concentrations as shown in vitro and following short-term exposure to high air pollution levels in vivo. Exposure to pollution during la
Costs and effects of the Tanzanian national voucher scheme for insecticide-treated nets (Publications)
BACKGROUND:The cost-effectiveness of insecticide-treated nets (ITNs) in reducing morbidity and mortality is well established. International focus has now moved on to how best to scale up coverage and
Allomonal effect of breath contributes to differential attractiveness of humans to the African malaria vector Anopheles gambiae (Publications)
BACKGROUND: Removal of exhaled air from total body emanations or artificially standardising carbon dioxide (CO2) outputs has previously been shown to eliminate differential attractiveness of humans to
Couple experiences of provider-initiated couple HIV testing in an antenatal clinic in Lusaka, Zambia: lessons for policy and practice (Publications)
BACKGROUND: Couple HIV testing has been recognized as critical to increase uptake of HIV testing, facilitate disclosure of HIV status to marital partner, improve access to treatment, care and support,
Advancing drug innovation for neglected diseases-criteria for lead progression (Publications)
The current drug R&D pipeline for most neglected diseases remains weak, and unlikely to support registration of novel drug classes that meet desired target product profiles in the short term. This cal
Interpreting malaria age-prevalence and incidence curves: a simulation study of the effects of different types of heterogeneity (Publications)
ABSTRACT: BACKGROUND: Individuals in a malaria endemic community differ from one another. Many of these differences, such as heterogeneities in transmission or treatment-seeking behaviour, affect mala
A systematic review of qualitative findings on factors enabling and deterring uptake of HIV testing in sub-Saharan Africa (Publications)
BACKGROUND: Despite Sub-Saharan Africa (SSA) being the epicenter of the HIV epidemic, uptake of HIV testing is not optimal. While qualitative studies have been undertaken to investigate factors influe
