Cost implications of improving malaria diagnosis: findings from north-eastern Tanzania (Publications)
diagnosis of malaria was estimated by comparing the proportion of outpatient attendees of all ages clinically diagnosed as malaria to the proportion of attendees having a positive malaria rapid diagnostic [...] diagnosis of malaria contributes to improper treatment, wastage of drugs and resistance to the few available drugs. This paper attempts to estimate the rates of over diagnosis of malaria among children
Behavioural determinants of gene flow in malaria vector population: <em>Anopheles gambiae</em> males select large females as mates (Publications)
transgenic vectors. Fundamental studies of behavioural ecology in malaria vectors such as An. gambiae can have important implications for malaria control and should be prioritised for more extensive investigation [...] BACKGROUND: Plasmodium-refractory mosquitoes are being rapidly developed for malaria control but will only succeed if they can successfully compete for mates when released into the wild. Pre-copulatory [...] structure in wild mosquito populations and mating barriers have foiled...
The combined effect of determinants on coverage of intermittent preventive treatment of malaria during pregnancy in the Kilombero Valley, Tanzania (Publications)
(ANC) clinics is an important and efficacious intervention to reduce adverse health outcomes of malaria infections during pregnancy. However, coverage for the recommended two IPTp doses is still far below [...] delivery practices and increase IPTp coverage. Pregnant women's knowledge about IPTp and the risks of malaria during pregnancy should be enhanced as well as their ability and power to demand IPTp and other ANC
<em>Plasmodium vivax</em> and mixed infections are associated with severe malaria in children: a prospective cohort study from Papua New Guinea (Publications)
prospective cohort study conducted within the framework of the Malaria Vaccine Epidemiology and Evaluation Project. All presumptive malaria cases presenting at two rural health facilities over an 8-y period [...] diagnosis of malaria associated with asexual blood stage parasitaemia and recent history of fits, or coma, or respiratory distress, or anaemia [haemoglobin < 5 g/dl]). Out of 17,201 presumptive malaria cases [...] BACKGROUND: Severe malaria (SM) is classically associated with Plasmodium...
Malaria and its possible control on the island of Príncipe (Publications)
BACKGROUND: Malaria can be eradicated from islands. To assess the prospects for eradication of malaria from the island of Príncipe in the Gulf of Guinea, we fitted a mathematical model to age-prevalence [...] nets and mosquito-proofing of dwellings. In contrast to traditional malaria eradication strategies, this would avoid the risk of malaria epidemics because the reduction in R0 should be sustainable. [...] thus obtained estimates of the vectorial capacity and of the basic reproductive number...
Malaria risk and access to prevention and treatment in the paddies of the Kilombero Valley, Tanzania (Publications)
BACKGROUND: The Kilombero Valley is a highly malaria-endemic agricultural area in south-eastern Tanzania. Seasonal flooding of the valley is favourable to malaria transmission. During the farming season, many [...] nearest health services. This study assessed the impact of seasonal movements to remote fields on malaria risk and treatment-seeking behaviour. METHODS: A longitudinal study followed approximately 100 randomly [...] fever-risk. Mosquito nets usage and treatment of fever in health...
