Michellamines A6 and A7, and further mono- and dimeric naphthylisoquinoline alkaloids from a Congolese <em>Ancistrocladus</em> liana and their... (Publications)
Michellamines A6 (1) and A7 (2) are the first dimers of 5,8′-coupled naphthylisoquinoline alkaloids with cis-configured stereocenters in both tetrahydroisoquinoline subunits. They were isolated from t
Insufficient fruit and vegetable intake in a low- and middle-income setting: a population-based survey in semi-urban Tanzania (Publications)
A daily intake of 5 portions of fruit and vegetables (FV) is recommended for protection against non-communicable diseases (NCDs). Inadequate FV intake is a global problem but resource-poor countries l
Georatusin, a specific antiparasitic polyketide-peptide hybrid from the gungus <em>Geomyces auratus</em> (Publications)
Georatusin (1), featuring a highly reduced, methylated polyketide moiety fused to a tryptophan by an amide and ester bond forming a 13-membered ring, was produced by the soil fungus Geomyces auratus.
Indoor bacteria and asthma in adults: a multicentre case-control study within ECRHS II (Publications)
Both protective and adverse effects of indoor microbial exposure on asthma have been reported, but mostly in children. To date, no study in adults has used non-targeted methods for detection of indoor
High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds (Publications)
Rapidly spreading antibiotic resistance and the low discovery rate of new antimicrobial compounds demand more effective strategies for early drug discovery. One bottleneck in the drug discovery pipeli
Time trends of positivity rates from foodborne pathogen testing in Switzerland, 2003 to 2012 (Publications)
BACKGROUND: Campylobacteriosis and salmonellosis are important foodborne diseases in Europe, including in Switzerland. In 2014, notification rates for Switzerland were 92.9 per 100 000 population for
Identification of steroid-like natural products as antiplasmodial agents by 2D and 3D similarity-based virtual screening (Publications)
The emergence of drug resistance in Plasmodium falciparum to available antimalarial drugs has challenged current antimalarial treatments. New antimalarials, particularly those with novel mechanisms of