Increase in diagnosed asthma but not in symptoms in the European Community Respiratory Health Survey (Publications)
BACKGROUND: Information on the epidemiology of asthma in relation to age is limited and hampered by reporting error. To determine the change in the prevalence of asthma with age in young adults we ana
Antimalarial activities of ferroquine conjugates with either glutathione reductase inhibitors or glutathione depletors via a hydrolyzable amide linker (Publications)
Based on the prodrug concept as well as the combination of two different classes of antimalarial agents, we designed and synthesized two series of ferrocenic antimalarial dual molecules consisting of
Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian <em>Aplidium scabellum</em> (Publications)
Bioassay-directed fractionation of an extract of the New Zealand ascidian Aplidium scabellum has afforded the anti-inflammatory secondary metabolite 2-geranyl-6-methoxy-1,4-hydroquinone-4-sulfate (1)
Praziquantel analogs with activity against juvenile<em> Schistosoma mansoni</em> (Publications)
Six amide and four urea derivatives of praziquantel were synthesized and tested for antischistosomal activity against juvenile and adults stages of Schistosoma mansoni in infected mice. Only one of th
Sequence and expression of MHC-DPB1 molecules of the new world monkey<em> Aotus nancymaae</em>, a primate model for <em>Plasmodium falciparum</em> 2 (Publications)
Aotus nancymaae represents an animal model for the pre-clinical evaluation of blood-stage vaccine candidates against Plasmodium falciparum and Plasmodium vivax. We present here the nucleotide sequence