Impact de l'urbanisation sur l'indice plasmodique et les densités parasitaires chez les enfants de 0 à 5 ans dans la commune de Yopougon, Abidjan... (Publications)
microscope after staining. The malaria infection rate was 21.8%, indicating mesoendemic malaria. Its distribution varied significantly between the three urbanization levels. Malaria parasite densities also varied [...] to determine the impact of urbanization on the malaria infection (parasite) rate and parasite density, and their consequences on the heterogeneity of malaria transmission in urban Abidjan. Specifically we [...] tly between them. These results confirm the involvement of...
Reactive Case Detection in Zanzibar: Effectiveness and Cost (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/reactive-case-detection-in-zanzibar-effectiveness-and-cost
have interrupted local malaria transmission and may have ceased to lead to further declines in malaria incidence. This project aims at contributing to the elimination of malaria on Zanzibar by providing [...] the burden of malaria by distributing insecticide treated mosquito nets, indoor residual spraying and artemisinin based combination treatment. Since 2008, Zanzibar has implemented the Malaria Epidemic Early [...] electronic surveillance system developed jointly by the Zanzibar Malaria...
Absence of dry season <em>Plasmodium</em> parasitaemia, but high rates of reported acute respiratory infection and diarrhoea in presschool-aged... (Publications)
epidemiology of malaria in the Senegal River Gorgol valley, southern Mauritania, requires particular attention in the face of ongoing and predicted environmental and climate changes. While "malaria cases" are [...] ons in neighbouring regions point to an absence of malaria transmission in mosquito vectors in the dry season. Because the clinical signs of malaria are non-specific and overlap with those of other diseases [...] diseases (e.g. acute respiratory infections and diarrhoea), new research...
A prospective study of <em>Plasmodium falciparum</em> multiplicity of infection and morbidity in Tanzanian children (Publications)
individuals with substantial previous exposure to malaria, co-infection with multiple clones of Plasmodium falciparum can protect against subsequent clinical malaria attacks. Other studies, mainly of individuals [...] These results provide further evidence that relationships between asymptomatic malaria infections and clinical malaria change with cumulative exposure. [...] multiplicity of infection increased with age. In the first year of life, the incidence of clinical malaria was almost three...
Genetic composition of Plasmodium falciparum infections in Zanzibar, travel and transmission: a follow-up to the RADZEC study (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/genetic-composition-of-plasmodium-falciparum-infections-in-zanzibar-travel-and-transmission-a-follow-up-to-the-radzec-study
investigations, we will analyse travel patterns of malaria patients and their household contacts to investigate associations of particular travel patterns with malaria infection status in general, and infection [...] Travel between Zanzibar and mainland Tanzania is likely to contribute substantially to the malaria case load on the islands of Zanzibar. In this study, we will investigate the genetic composition of P [...] in particular. This will be complemented by modeling of the improtance of...
Disease Modelling | Research at Swiss TPH (Page)
https://www.swisstph.ch/de/about/eph/disease-modelling
Projects Core Malaria Software for Modellers Worldwide Core to our modelling work is the development and use of an individual-based model of malaria transmission dynamics known as OpenMalaria. This model [...] tool for simulating the dynamics of malaria transmission and epidemiology, and the impact of interventions on health and economic outcomes. The model can simulate malaria in village or district size human [...] TPH, our OpenMalaria model is used by a wide range of modellers worldwide. A...
Rapid spread of double East- and West-African <em>kdr </em>mutations in wild <em>Anopheles coluzzi</em> from Côte d'Ivoire (Publications)
decrease of malaria burden. These tools are now threatened by insecticide resistance in malaria vectors, which is spreading dramatically. After two different real-time polymerase chain reaction molecular char [...] resistance in malaria vectors and highlight the urgent need to diversify the methods of vector control in order to avoid the failure of insecticide-based vector control tools which may favor malaria fatalities [...] Malaria morbidity and mortality rates in Sub-Saharan Africa are...
The risk of malarial infections and disease in Papua New Guinean children (Publications)
vivax = 5.28), they were 21 times more likely to develop symptomatic P. falciparum malaria (1.17/year) than P. vivax malaria (0.06/year). Children greater than nine years of age had a reduced risk of acquiring [...] to symptomatic P. falciparum malaria remained incomplete. These observations suggest that different mechanisms of immunity may be important for protection from these malaria species [...] study of 206 Papua New Guinean school children, we examined risk of reinfection and symptomatic ...
Identifying risk factors for <em>Plasmodium </em>infection and anaemia in Kinshasa, Democratic Republic of Congo (Publications)
risk factors for malaria infection in large cities in central Africa and in all age groups. There may be different associations with the risk factors for areas with different malaria transmission intensities [...] (non-rural), collected during a cross sectional malaria survey in 2011. Logistic regression with random effects was used to investigate predictors for malaria and anaemia. Differences in risk factors in areas [...] whereas it increased with malaria infection and reported fever. ITN use...
Analysis and mapping of prospective sources of funding for additional contributions to MEMTI (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/analysis-and-mapping-of-prospective-sources-of-funding-for-additional-contributions-to-memti
The Global Fund to Fight AIDS, Tuberculosis and Malaria set aside funding to incentivize the acceleration of efforts towards elimination of malaria in four countries in the Asia-Pacific region: Papua New [...] New Guinea, Solomon Islands, Vanuatu and Timor-Leste. This "Malaria Elimination in Melanesia and Timor-Leste Initiative" (MEMTI) is additional to Global Fund country funding allocations and is intended [...] development partners. Regarding the identification of all sources of funding for...