Efficacy and safety of tribendimidine versus praziquantel against <em>Opisthorchis viverrini</em> in Laos: an open-label, randomised, non-inferiority,... (Publications)
praziquantel administered in two doses, in participants with O viverrini infection. METHOD: We did an open-label, randomised, non-inferiority, phase 2 trial in children (8-14 years) and adolescents and adults
SMSs as an alternative to provider-delivered care for unhealthy alcohol use: study protocol for <em>Leseli</em>, an open-label randomised controlled... (Publications)
use (as detailed by the primary and secondary outcomes below). METHODS: This is a two-arm randomised open-label multicentre superiority trial. Participants allocated to mhGAP-Standard receive 4 in-person
Feasibility and acceptability of the Problem Management for Moms programme for improving maternal mental health in Zambia: an open-label trial (Publications)
adapted psychosocial intervention for distressed mothers in low-resource settings. METHODS: In this open-label trial, we enrolled women living in Lusaka, Zambia, with high mental distress (> 7 score on the
Efficacy and safety of albendazole alone versus albendazole in combination with ivermectin for the treatment of Trichuris trichiura infections: an... (Publications)
necessary to evaluate the performance of the combination before introducing it on a larger scale. This open-label, randomized controlled superiority trial in two Ugandan primary schools enrolled eligible 6-
The impact of home-installed growth charts and small-quantity lipid-based nutrient supplements (SQ-LNS) on child growth in Zambia: a four-arm parallel... (Publications)
BACKGROUND: Childhood stunting remains common in many low-income settings and is associated with increased morbidity and mortality, as well as impaired child development. METHODS: The main objective o
Hepatitis A vaccine for immunosuppressed patients with rheumatoid arthritis: a prospective, open-label, multi-centre study (Publications)
BACKGROUND: Hepatitis A vaccine is the most frequently used travel vaccine, yet data are scarce about its ability to induce protection in patients with concurrent immunosuppressive treatment. We asses
Open Malaria : a simulator program for studying malaria epidemiology and the impacts of interventions against malaria [Software] (Publications)
OpenMalaria is an open source C++ program for simulating malaria epidemiology and the impacts on that epidemiology of interventions against malaria. It is based on microsimulations of
Fixed-dose artesunate-amodiaquine combination vs chloroquine for treatment of uncomplicated blood stage <em>P. vivax</em> infection in the Brazilian... (Publications)
BACKGROUND: Despite increasing evidence of the development of Plasmodium vivax chloroquine (CQ) resistance, there have been no trials comparing its efficacy with that of artemisinin-based combination
