Heterologous production and functional characterization of ageritin, a novel type of ribotoxin highly expressed during fruiting of the edible mushroom... (Publications)
Fungi produce various defense proteins against antagonists including ribotoxins. These toxins cleave a single phosphodiester bond within the universally conserved sarcin-ricin loop of ribosomes and in
The impact of pastoralist mobility on tuberculosis control in Ethiopia: a systematic review and meta-synthesis (Publications)
BACKGROUND: Directly observed treatment, short-course (DOTS) is the current mainstay to control tuberculosis (TB) worldwide. Context-specific adaptations of DOTS have impending implications in the fig
"There is a cat on our ward": inpatient and staff member attitudes toward and experiences with cats in a psychiatric ward (Publications)
The aim of this study was to investigate inpatient and staff member attitudes toward and experiences with ward cats, and identify possible mechanisms for how cats affect patient satisfaction in a psyc
Validation of the protein kinase <em>Pf</em>CLK3 as a multistage cross-species malarial drug target (Publications)
The requirement for next-generation antimalarials to be both curative and transmission-blocking necessitates the identification of previously undiscovered druggable molecular pathways. We identified a
The viral load monitoring cascade in a resource-limited setting: a prospective multicentre cohort study after introduction of routine viral load... (Publications)
INTRODUCTION: For HIV-positive individuals on antiretroviral therapy (ART), the World Health Organization (WHO) recommends routine viral load (VL) monitoring. We report on the cascade of care in indiv
Short course amphotericin B in addition to sertraline and fluconazole for treatment of HIV-associated cryptococcal meningitis in rural Tanzania (Publications)
BACKGROUND: Cryptococcal meningitis accounts for 15% of all AIDS-mortality globally. Most cases in low- and middle-income countries are treated with fluconazole monotherapy, which is associated with a
Dog ecology, bite incidence, and disease awareness: a cross-sectional survey among a rabies-affected community in the Democratic Republic of the Congo (Publications)
Despite the existence of safe and efficacious human and animal rabies vaccines, millions of people remain at risk of exposure to this deadly zoonotic disease through bites of infected dogs. Sub-Sahara
Fluorescence in situ hybridization (FISH) for rapid identification of <em>Salmonella</em> spp. from agar and blood culture broth--an option for the... (Publications)
BACKGROUND: Salmonella enterica is an important cause of diarrhea with the potential to cause systemic infection including sepsis, particularly in the tropics. Sepsis in particular requires quick and